HLA-B55

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major histocompatibility complex (human), class I, B55
Alleles B*5501, B*5502
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5501
B*5502
Locus chr.6 6p21.31

HLA-B55 (B55) is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products.[1] (For terminology help see: HLA-serotype tutorial)

Serotype[edit]

B55 and B22 serotype recognition of some HLA B*55 allele-group gene products[2]
B*55 B55 B22 Sample
allele  %  % size (N)
5501 92 5 453
5502 84 2 309

Allele distribution[edit]

HLA B*5501 frequencies
freq
ref. Population (%)
[3] India New Delhi 3.8
[3] Singapore Chinese Han 3.5
[3] Spain Eastern Andalusia Gipsy 3.5
[3] Georgia Tibilisi Kurds 3.4
[3] India North Delhi 3.3
[3] France South East 3.1
[3] Israel Arab Druse 3.0
[3] India North Hindus 2.9
[3] Georgia Tibilisi Georgians 2.8
[3] Russia Tuva (2) 2.8
[3] Georgia Svaneti Svans 2.5
[3] Iran Baloch 2.5
[3] Singapore Thai 2.5
[3] Sudanese 2.5
[3] Mexico Mestizos 2.4
[3] Spain Eastern Andalusia 2.4
[3] Ireland South 2.0
[3] Azores Central Islands 1.8
[3] Bulgaria 1.8
[3] Israel Ashkenazi and Non Ashkenazi Jews 1.8
[3] Oman 1.7
[3] Tunisia Tunis 1.7
[3] India Andhra Pradesh Golla 1.4
[3] China Tibet 1.3
[3] Uganda Kampala 1.2
[3] Finland 1.1
[3] Portugal North 1.1
[3] Portugal Centre 1.0
[3] Singapore Riau Malay 1.0
[3] B*5502
[3] Taiwan Taroko 14.5
[3] American Samoa 12.0
[3] China Guangxi Maonan 6.0
[3] Japan Ainu Hokkaido 5.0
[3] China Tibet Autonomous Region Tibetans 4.7
[3] Singapore Chinese 3.0
[3] China Beijing Shijiazhuang Tianjian Han 2.9
[3] China North Han 2.9
[3] South Korea (3) 2.7
[3] Hong Kong Chinese 2.2
[3] Japan (5) 2.2
[3] Taiwan Ami 2.0
[3] Thailand (3) 2.0
[3] New Caledonia 1.0
[3] Philippines Ivatan 1.0

References[edit]

  1. ^ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720. 
  2. ^ derived from IMGT/HLA
  3. ^ a b c d e f g h i j k l m n o p q r s t u v w x y z aa ab ac ad ae af ag ah ai aj ak al am an ao ap aq ar as Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.