HLA-B59

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major histocompatibility complex (human), class I, B59
Alleles B*5901
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5901
Locus chr.6 6p21.31

HLA-B59 (B59) is an HLA-B serotype. The serotype identifies the more common HLA-B*## gene products.[1] B59 is a hybrid between B*55 and B*51.[2] B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)

Serotype[edit]

B59 serotype recognition of the HLA B*59 allele-group gene products[3]
B*59 B59 Other Sample
allele  %  % size (N)
5901 45 41 123

B*5901 allele frequencies[edit]

HLA B*5901 frequencies
freq
ref. Population (%)
[4] Okinawan (USA Hawaii) 6.3
[4] Japan (2) 2.7
[4] Tarialan Khoton (Mongolia) 2.4
[4] South Korea (3) 2.1
[4] Gipuscoa Basque (Spain) 2.0
[4] Japan Central 1.8
[4] Casablanca (Morocco) 1.8
[4] Hyogo (Japan) 1.6
[4] N. Korean (Harbin,China) 1.0
[4] Manchu (Harbin, China) 0.6
[4] Naxi (Yunnan, China) 0.6
[4] Girona (Catalonia,Spain) 0.6
[4] Algeria (1) 0.5
[4] Inner Mongolia (China) 0.5
[4] Khalkha (Mongolia) 0.5
[4] Shanghai (China) 0.3
[4] Essen (German ) 0.3
[4] Southern Han (China) 0.2
[4] Shij. Tian. (Beijing, China) 0.1
[4] Hakka (Taiwan) 0.1
Regions of higher B*5901 frequency
Japan LocationMapJapan.png
Korea Locator map of South Korea.svg
Mongolia Location of Mongolia.svg
Heilongjiang
prov., China
(Harbin city)
China-Heilongjiang.png

References[edit]

  1. ^ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720. 
  2. ^ Hildebrand WH, Domena JD, Parham P (1993). "Primary structure shows HLA-B59 to be a hybrid of HLA-B55 and HLA-B51, and not a subtype of HLA-B8". Tissue Antigens 41 (4): 190–5. doi:10.1111/j.1399-0039.1993.tb02001.x. PMID 8362411. 
  3. ^ derived from IMGT/HLA
  4. ^ a b c d e f g h i j k l m n o p q r s t Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.