HMCN1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
HMCN1
Identifiers
Aliases HMCN1, ARMD1, FBLN6, FIBL-6, FIBL6, hemicentin 1
External IDs MGI: 2685047 HomoloGene: 23741 GeneCards: HMCN1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_031935

NM_001024720

RefSeq (protein)

NP_114141

NP_001019891

Location (UCSC) Chr 1: 185.73 – 186.19 Mb Chr 1: 150.56 – 150.99 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Hemicentin-1 is a protein that in humans is encoded by the HMCN1 gene.[3][4]

This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Vogel BE, Hedgecock EM (Mar 2001). "Hemicentin, a conserved extracellular member of the immunoglobulin superfamily, organizes epithelial and other cell attachments into oriented line-shaped junctions". Development. 128 (6): 883–94. PMID 11222143. 
  4. ^ a b "Entrez Gene: HMCN1 hemicentin 1". 

Further reading[edit]