Chromosomal protein HMG14 and its close analog HMG17 (MIM 163910) bind to the inner side of the nucleosomal DNA, potentially altering the interaction between the DNA and the histone octamer. The 2 proteins may be involved in the process that maintains transcribable genes in a unique chromatin conformation. Their ubiquitous distribution and relative abundance, as well as the high evolutionary conservation of the DNA-binding domain of the HMG14 family of proteins, suggest that they may be involved in an important cellular function.[supplied by OMIM]
^Landsman D, Srikantha T, Westermann R, Bustin M (Dec 1986). "Chromosomal protein HMG-14. Complete human cDNA sequence and evidence for a multigene family". The Journal of Biological Chemistry261 (34): 16082–6. PMID3782107.
^Landsman D, McBride OW, Soares N, Crippa MP, Srikantha T, Bustin M (Feb 1989). "Chromosomal protein HMG-14. Identification, characterization, and chromosome localization of a functional gene from the large human multigene family". The Journal of Biological Chemistry264 (6): 3421–7. PMID2563381.
Postnikov YV, Trieschmann L, Rickers A, Bustin M (Sep 1995). "Homodimers of chromosomal proteins HMG-14 and HMG-17 in nucleosome cores". Journal of Molecular Biology252 (4): 423–32. doi:10.1006/jmbi.1995.0508. PMID7563062.
Ding HF, Rimsky S, Batson SC, Bustin M, Hansen U (Aug 1994). "Stimulation of RNA polymerase II elongation by chromosomal protein HMG-14". Science265 (5173): 796–9. doi:10.1126/science.8047885. PMID8047885.
Pash JM, Alfonso PJ, Bustin M (Jun 1993). "Aberrant expression of high mobility group chromosomal protein 14 affects cellular differentiation". The Journal of Biological Chemistry268 (18): 13632–8. PMID8514795.
Bustin M, Alfonso PJ, Pash JM, Ward JM, Gearhart JD, Reeves RH (Dec 1995). "Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin". DNA and Cell Biology14 (12): 997–1005. doi:10.1089/dna.1995.14.997. PMID8534374.
Bergel M, Herrera JE, Thatcher BJ, Prymakowska-Bosak M, Vassilev A, Nakatani Y, Martin B, Bustin M (Apr 2000). "Acetylation of novel sites in the nucleosomal binding domain of chromosomal protein HMG-14 by p300 alters its interaction with nucleosomes". The Journal of Biological Chemistry275 (15): 11514–20. doi:10.1074/jbc.275.15.11514. PMID10753971.
Zou Y, Jiang X, Wang Y (May 2004). "Identification of novel in vivo phosphorylation sites in high mobility group N1 protein from the MCF-7 human breast cancer cells". Biochemistry43 (20): 6322–9. doi:10.1021/bi0362828. PMID15147216.