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High mobility group nucleosomal binding domain 4
Symbols HMGN4 ; HMG17L3; NHC
External IDs MGI3708112 HomoloGene105484 GeneCards: HMGN4 Gene
Species Human Mouse
Entrez 10473 633596
Ensembl ENSG00000182952 n/a
UniProt O00479 n/a
RefSeq (mRNA) NM_006353 n/a
RefSeq (protein) NP_006344 n/a
Location (UCSC) Chr 6:
26.54 – 26.55 Mb
PubMed search [1] [2]

High mobility group nucleosome-binding domain-containing protein 4 is a transcription factor that in humans is encoded by the HMGN4 gene.[1][2]


The protein encoded by this gene, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Transcript variants utilizing alternative polyadenylation signals exist for this gene.[1]

See also[edit]


  1. ^ a b "Entrez Gene: high mobility group nucleosomal binding domain 4". 
  2. ^ Birger Y, Ito Y, West KL, Landsman D, Bustin M (May 2001). "HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene". DNA Cell Biol. 20 (5): 257–64. doi:10.1089/104454901750232454. PMID 11410162. 

Further reading[edit]