HMGN4

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HMGN4
Identifiers
AliasesHMGN4, HMG17L3, NHC, high mobility group nucleosomal binding domain 4
External IDsHomoloGene: 105484 GeneCards: HMGN4
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for HMGN4
Genomic location for HMGN4
Band6p22.2Start26,538,405 bp[1]
End26,546,254 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006353

n/a

RefSeq (protein)

NP_006344
NP_006344.1

n/a

Location (UCSC)Chr 6: 26.54 – 26.55 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

High mobility group nucleosome-binding domain-containing protein 4 is a transcription factor that in humans is encoded by the HMGN4 gene.[3][4]

Function[edit]

The protein encoded by this gene, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Transcript variants utilizing alternative polyadenylation signals exist for this gene.[3]

See also[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000182952 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:".
  3. ^ a b "Entrez Gene: high mobility group nucleosomal binding domain 4".
  4. ^ Birger Y, Ito Y, West KL, Landsman D, Bustin M (May 2001). "HMGN4, a newly discovered nucleosome-binding protein encoded by an intronless gene". DNA Cell Biol. 20 (5): 257–64. doi:10.1089/104454901750232454. PMID 11410162.

Further reading[edit]