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Homeobox A4
Symbols HOXA4 ; HOX1; HOX1D
External IDs OMIM142953 MGI96176 HomoloGene37583 GeneCards: HOXA4 Gene
RNA expression pattern
PBB GE HOXA4 206289 at tn.png
More reference expression data
Species Human Mouse
Entrez 3201 15401
Ensembl ENSG00000197576 ENSMUSG00000000942
UniProt Q00056 P06798
RefSeq (mRNA) NM_002141 NM_008265
RefSeq (protein) NP_002132 NP_032291
Location (UCSC) Chr 7:
27.13 – 27.13 Mb
Chr 6:
52.19 – 52.19 Mb
PubMed search [1] [2]

Homeobox A4, also known as HOXA4, is a protein which in humans is encoded by the HOXA4 gene.[1][2]


In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes.[3] Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.[1]

See also[edit]


  1. ^ a b "Entrez Gene: HOXA4 homeobox A4". 
  2. ^ McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146. 
  3. ^ Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.