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Homeobox B2
Symbols HOXB2 ; HOX2; HOX2H; Hox-2.8; K8
External IDs OMIM142967 MGI96183 HomoloGene37584 GeneCards: HOXB2 Gene
RNA expression pattern
PBB GE HOXB2 205453 at tn.png
More reference expression data
Species Human Mouse
Entrez 3212 103889
Ensembl ENSG00000173917 ENSMUSG00000075588
UniProt P14652 P0C1T1
RefSeq (mRNA) NM_002145 NM_134032
RefSeq (protein) NP_002136 NP_598793
Location (UCSC) Chr 17:
48.54 – 48.54 Mb
Chr 11:
96.35 – 96.35 Mb
PubMed search [1] [2]

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.[1][2][3]


This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.[3]

See also[edit]


  1. ^ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146. 
  2. ^ Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. 
  3. ^ a b "Entrez Gene: HOXB2 homeobox B2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.