HOXB2

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HOXB2
Identifiers
Aliases HOXB2, HOX2, HOX2H, Hox-2.8, K8, homeobox B2
External IDs MGI: 96183 HomoloGene: 37584 GeneCards: 3212
RNA expression pattern
PBB GE HOXB2 205453 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002145

NM_134032

RefSeq (protein)

NP_002136.1

NP_598793.2

Location (UCSC) Chr 17: 48.54 – 48.54 Mb Chr 11: 96.35 – 96.35 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.[3][4][5]

Function[edit]

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146. 
  4. ^ Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. 
  5. ^ a b "Entrez Gene: HOXB2 homeobox B2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.