HPSE2

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HPSE2
Identifiers
Aliases HPSE2, HPA2, HPR2, UFS, UFS1, heparanase 2 (inactive)
External IDs MGI: 2685814 HomoloGene: 19680 GeneCards: HPSE2
Genetically Related Diseases
asthma, obesity[1]
RNA expression pattern
PBB GE HPSE2 220927 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001166244
NM_001166245
NM_001166246
NM_021828

NM_001081257

RefSeq (protein)

NP_001159716
NP_001159717
NP_001159718
NP_068600

NP_001074726.1
NP_001074726

Location (UCSC) Chr 10: 98.46 – 99.24 Mb Chr 19: 42.79 – 43.39 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Heparanase-2 is an enzyme that in humans is encoded by the HPSE2 gene.[4][5]


It may be associated with urofacial syndrome.[6]

References[edit]

  1. ^ "Diseases that are genetically associated with HPSE2 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ McKenzie E, Tyson K, Stamps A, Smith P, Turner P, Barry R, Hircock M, Patel S, Barry E, Stubberfield C, Terrett J, Page M (Oct 2000). "Cloning and expression profiling of Hpa2, a novel mammalian heparanase family member". Biochem Biophys Res Commun. 276 (3): 1170–7. doi:10.1006/bbrc.2000.3586. PMID 11027606. 
  5. ^ "Entrez Gene: HPSE2 heparanase 2". 
  6. ^ Daly SB, Urquhart JE, Hilton E, et al. (June 2010). "Mutations in HPSE2 Cause Urofacial Syndrome". Am J Hum Genet. 86 (6): 963–969. doi:10.1016/j.ajhg.2010.05.006. PMC 3032078Freely accessible. PMID 20560210. 

Further reading[edit]