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For GroEL/60 kDa heat shock protein with the same symbol, see GroEL.
Heat shock 70kDa protein 14
Symbols HSPA14 ; HSP70-4; HSP70L1
External IDs OMIM610369 MGI1354164 HomoloGene74307 GeneCards: HSPA14 Gene
RNA expression pattern
PBB GE HSPA14 219212 at tn.png
More reference expression data
Species Human Mouse
Entrez 51182 50497
Ensembl ENSG00000187522 ENSMUSG00000051396
UniProt Q0VDF9 Q99M31
RefSeq (mRNA) NM_001037538 NM_001037542
RefSeq (protein) NP_001265134 NP_056580
Location (UCSC) Chr 10:
14.84 – 14.87 Mb
Chr 2:
3.49 – 3.51 Mb
PubMed search [1] [2]

Heat shock 70 kDa protein 14 also known as HSP70-like protein 1 or heat shock protein HSP60 is a protein that in humans is encoded by the HSPA14 gene.[1][2]


  1. ^ Wan T, Zhou X, Chen G, An H, Chen T, Zhang W, Liu S, Jiang Y, Yang F, Wu Y, Cao X (March 2004). "Novel heat shock protein Hsp70L1 activates dendritic cells and acts as a Th1 polarizing adjuvant". Blood 103 (5): 1747–54. doi:10.1182/blood-2003-08-2828. PMID 14592822. 
  2. ^ "Entrez Gene: HSPA14 heat shock 70kDa protein 14". 

Further reading[edit]

  • Furlini G, Vignoli M, Re MC, et al. (1994). "Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.". J. Gen. Virol. 75 (1): 193–9. doi:10.1099/0022-1317-75-1-193. PMID 7906708. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
  • Scheufler C, Brinker A, Bourenkov G, et al. (2000). "Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine.". Cell 101 (2): 199–210. doi:10.1016/S0092-8674(00)80830-2. PMID 10786835. 
  • Lim MC, Brooke SM, Sapolsky RM (2003). "gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.". Brain Res. Bull. 61 (2): 183–8. doi:10.1016/S0361-9230(03)00113-8. PMID 12832005. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. 

External links[edit]