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Protein HUWE1 PDB 2EKK.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases HUWE1, ARF-BP1, HECTH9, HSPC272, Ib772, LASU1, MULE, URE-B1, UREB1, HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
External IDs MGI: 1926884 HomoloGene: 45994 GeneCards: HUWE1
Gene location (Human)
X chromosome (human)
Chr. X chromosome (human)[1]
X chromosome (human)
Genomic location for HUWE1
Genomic location for HUWE1
Band Xp11.22 Start 53,532,096 bp[1]
End 53,686,729 bp[1]
RNA expression pattern
PBB GE HUWE1 208598 s at fs.png

PBB GE HUWE1 214673 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr X: 53.53 – 53.69 Mb Chr X: 151.8 – 151.94 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

E3 ubiquitin-protein ligase HUWE1 is an enzyme that in humans is encoded by the HUWE1 gene.[5][6][7]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000086758 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025261 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Sep 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841. 
  6. ^ Jackson PK, Eldridge AG, Freed E, Furstenthal L, Hsu JY, Kaiser BK, Reimann JD (Nov 2000). "The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases". Trends Cell Biol. 10 (10): 429–39. doi:10.1016/S0962-8924(00)01834-1. PMID 10998601. 
  7. ^ "Entrez Gene: HUWE1 HECT, UBA and WWE domain containing 1". 

Further reading[edit]

External links[edit]