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Hadrianus may refer to:
- Hadrian (76–138 CE), Roman emperor
- C. Fabius Hadrianus (fl. 80s BCE), Roman colonial administrator & politician
- Pope Adrian (disambiguation) (any of the listed popes)
- Hadrianus Junius (1511–1575), also known as Adriaen de Jonghe
| disambiguation page lists articles associated with the title Hadrianus.
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