|Chemical and physical data|
|Molar mass||598.69 g/mol|
|3D model (JSmol)|
|Melting point||172.5 °C (342.5 °F)|
Hematoporphyrin (Photodyn, Sensibion) is a porphyrin prepared from hemin. It is a derivative of protoporphyrin IX, where the two vinyl groups have been hydrated (coverted to alcohols). It is a deeply colored solid that is usually encountered as a solution. Its chemical structure was determined in 1900.
It is used as a photosensitizer in photodynamic therapy. Acetylation of hematoporphyrin followed by hydrolysis of the product of that reaction affords a mixture called hematoporphyrin derivative (HPD), which is also used in photodynamic therapy.
- "SpringerLink - Journal Article".
- David Kessel (1984). "Hematoporphyrin and HPD: Photophysics, Photochemistry And Phototherapy". Photochemistry and Photobiology. 39: 851–859. doi:10.1111/j.1751-1097.1984.tb08871.x.
- O'Neil, Maryadele J. (2001). The Merck index: an encyclopedia of chemicals, drugs, and biologicals. Rahway, NJ: Merck Research Laboratories. ISBN 0-911910-13-1.
- "Hematoporphyrin as a Therapeutic Agent in the Psychoses -- Strecker et al. 90 (6): 1157 -- Am J Psychiatry".
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