Possible place of origin
Q-L54, Q-M323 
L56, L57, M346
Haplogroup Q-M346 is a subclade of Y-DNA Haplogroup Q. Haplogroup Q-M346 is defined by the presence of the M346 Single Nucleotide Polymorphism (SNP).
Origin and distribution [ edit ]
Q-M346 was discovered in Central Asia and announced in Sengupta 2006.
A latter paper suggested that its ancestral state was isolated to India,  but this has since been refuted by its presence in West Asia,  Europe and the Americas.  
Q-M346 has a wide distribution across much of Asia.
   
The Americas [ edit ]
In the Americas, the founding paternal lineages include those who are Q-M346 but do not belong to the Q-M3 lineage.
Associated SNPs [ edit ]
Q-M346 is marked by the presence of the M346 SNP. Since the discovery of M346 several additional SNPs have been found to also be associated with Q-M346. These SNP's include: L56 and L57. These SNPs appear to be "parallel" to M346.
Subgroups [ edit ]
This is Thomas Krahn at the Genomic Research Center's Draft tree
Proposed Tree for haplogroup Q-M346. The first three levels of subclades are shown. Additional detail is provided on the linked branch article pages. 
Q-MEH2 MEH2, L472, L528
Q-M346 M346, L56, L57, L474, L892, L942
Q-L717 L717, L718
Q-L527 L527, L529, L639
Q-L933 L933, L938, L941
Q-L53 L53, L55, L213, L331, L475, L476
See also [ edit ]
Y-DNA Q-M242 subclades [ edit ]
Y-DNA backbone tree [ edit ]
Phylogenetic tree of human
Y-chromosome DNA haplogroups [χ 1] [χ 2]
LT [χ 5]
T [χ 6]
K2a [χ 7]
K2b [χ 8]
K2e [χ 9]
K2b1 [χ 10]
P [χ 11]
S [χ 12]
M [χ 13]
^ Van Oven M, Van Geystelen A, Kayser M, Decorte R, Larmuseau HD (2014). "Seeing the wood for the trees: a minimal reference phylogeny for the human Y chromosome". Human Mutation. 35 (2): 187–91. doi: 10.1002/humu.22468. PMID 24166809.
^ International Society of Genetic Genealogy (ISOGG; 2015), . (Access date: 1 February 2015.) Y-DNA Haplogroup Tree 2015
^ Haplogroup A0-T is also known as A0'1'2'3'4.
^ Haplogroup A1 is also known as A1'2'3'4.
^ Haplogroup LT (L298/P326) is also known as Haplogroup K1.
^ Between 2002 and 2008, Haplogroup T (M184) was known as "Haplogroup K2" – that name has since been re-assigned to K-M526, the sibling of Haplogroup LT.
^ Haplogroup K2a (M2308) and the new subclade K2a1 (M2313) were separated from Haplogroup NO (F549) in 2016. (This followed the publication of: Poznik GD, Xue Y, Mendez FL, et al. (2016). "Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences". Nature Genetics. 48 (6): 593–9. doi: 10.1038/ng.3559. PMC . 4884158 PMID 27111036. In the past, other haplogroups, including NO1 (M214) and K2e had also been identified with the name "K2a".
^ Haplogroup K2b (M1221/P331/PF5911) is also known as Haplogroup MPS.
^ Haplogroup K2e (K-M147) was previously known as "Haplogroup X" and "K2a" (but is a sibling subclade of the present K2a).
^ Haplogroup K2b1 (P397/P399) is also known as Haplogroup MS, but has a broader and more complex internal structure.
^ Haplogroup P (P295) is also klnown as K2b2.
^ Haplogroup S, as of 2017, is also known as K2b1a. (Previously the name Haplogroup S was assigned to K2b1a4.)
^ Haplogroup M, as of 2017, is also known as K2b1b. (Previously the name Haplogroup M was assigned to K2b1d.)
References [ edit ]
^ a b c d e Krahn, Thomas. "FTDNA Draft Y-DNA Tree (AKA YTree)". Family Tree DNA . Retrieved 2012.
^ a b c d e f Sengupta, Sanghamitra; Zhivotovsky, Lev A.; King, Roy; Mehdi, S.Q.; Edmonds, Christopher A.; Chow, Cheryl-Emiliane T.; Lin, Alice A.; Mitra, Mitashree; Sil, Samir K. (2006). "Polarity and Temporality of High-Resolution Y-Chromosome Distributions in India Identify Both Indigenous and Exogenous Expansions and Reveal Minor Genetic Influence of Central Asian Pastoralists". The American Journal of Human Genetics. 78 (2): 202–21. doi: 10.1086/499411. PMC . 1380230 PMID 16400607.
^ Sharma, Swarkar; Rai, Ekta; Bhat, Audesh K; Bhanwer, Amarjit S; Bamezai, Rameshwar NK (2007). "A novel subgroup Q5 of human Y-chromosomal haplogroup Q in India". BMC Evolutionary Biology. 7: 232. doi: 10.1186/1471-2148-7-232. PMC . 2258157 PMID 18021436.
^ Abu-Amero, Khaled K; Hellani, Ali; González, Ana M; Larruga, Jose M; Cabrera, Vicente M; Underhill, Peter A (2009). "Saudi Arabian Y-Chromosome diversity and its relationship with nearby regions". BMC Genetics. 10: 59. doi: 10.1186/1471-2156-10-59. PMC . 2759955 PMID 19772609.
^ a b c d e f g h i j k l Bailliet, Graciela; Ramallo, Virginia; Muzzio, Marina; García, Angelina; Santos, María R.; Alfaro, Emma L.; Dipierri, José E.; Salceda, Susana; Carnese, Francisco R. (2009). "Brief communication: Restricted geographic distribution for Y-Q* paragroup in South America". American Journal of Physical Anthropology. 140 (3): 578–82. doi: 10.1002/ajpa.21133. PMID 19591214.
^ a b c d e f g Malyarchuk, Boris; Derenko, Miroslava; Denisova, Galina; Maksimov, Arkady; Wozniak, Marcin; Grzybowski, Tomasz; Dambueva, Irina; Zakharov, Ilya (2011). "Ancient links between Siberians and Native Americans revealed by subtyping the Y chromosome haplogroup Q1a". Journal of Human Genetics. 56 (8): 583–8. doi: 10.1038/jhg.2011.64. PMID 21677663.
^ a b K. Abu-Amero, Khaled; et al. (2009). "Saudi Arabian Y-Chromosome diversity and its relationship with nearby regions". BMC Genetics. 10: 59. doi: 10.1186/1471-2156-10-59. PMC . 2759955 PMID 19772609.
^ a b Dulik, Matthew C.; Osipova, Ludmila P.; Schurr, Theodore G. (2011). Kayser, Manfred, ed. "Y-Chromosome Variation in Altaian Kazakhs Reveals a Common Paternal Gene Pool for Kazakhs and the Influence of Mongolian Expansions". PLoS ONE. 6 (3): e17548. doi: 10.1371/journal.pone.0017548. PMC . 3055870 PMID 21412412.
^ a b c Dulik, Matthew C.; Zhadanov, Sergey I.; Osipova, Ludmila P.; Askapuli, Ayken; Gau, Lydia; Gokcumen, Omer; Rubinstein, Samara; Schurr, Theodore G. (2012). "Mitochondrial DNA and Y Chromosome Variation Provides Evidence for a Recent Common Ancestry between Native Americans and Indigenous Altaians". The American Journal of Human Genetics. 90 (2): 229–46. doi: 10.1016/j.ajhg.2011.12.014. PMC . 3276666 PMID 22281367.
^ Bisso-Machado, Rafael; Jota, Marilza S.; Ramallo, Virginia; Paixão-Côrtes, Vanessa R.; Lacerda, Daniela R.; Salzano, Francisco M.; Bonatto, Sandro L.; Santos, Fabrício R.; Bortolini, Maria Cátira (2011). "Distribution of Y-chromosome q lineages in native americans". American Journal of Human Biology. 23 (4): 563–6. doi: 10.1002/ajhb.21173. PMID 21544893.
External links [ edit ]