Harmonic scalpel

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The Harmonic scalpel is a surgical instrument used to simultaneously cut and cauterize tissue. Unlike Electrosurgery, the harmonic uses ultrasonic vibrations instead of electric current to cut and cauterize tissue.

Medical use[edit]

The harmonic scalpel may be superior to electrosurgery in that it can cut through thicker tissue, creates less toxic surgical smoke,.[1]


A Harmonic scalpel cuts via vibration. The scalpel surface itself cuts through tissue by vibrating in the range of 55,500 Hz. The high frequency vibration of tissue molecules generates stress and friction in tissue, which generates heat and causes protein denaturation. This technique causes minimal energy transfer to surrounding tissue, potentially limiting collateral damage.[2]


The Harmonic brand is manufactured in Mexico and distributed by Ethicon Endo-Surgery a subsidiary of Johnson & Johnson.

See also[edit]


  1. ^ Fitzgerald JE, Malik M, Ahmed I (2012). "A single blind controlled study of electrocautery and ultrasonic scalpel smoke plumes in laparoscopic surgery". Surgical Endoscopy. 26 (2): 337–342. doi:10.1007/s00464-011-1872-1. PMID 21898022.
  2. ^ Sabiston Textbook of Surgery. 2012. p. 236. ISBN 978-1-4377-1560-6.

Further reading[edit]

  • Msika S, Deroide G, Kianmanesh R, et al. (March 2001). "Harmonic scalpel in laparoscopic colorectal surgery". Dis. Colon Rectum. 44 (3): 432–6. doi:10.1007/bf02234745. PMID 11289292.
  • Awwad JT, Isaacson K (October 1996). "The harmonic scalpel: an intraoperative complication". Obstet Gynecol. 88 (4 Pt 2): 718–20. doi:10.1016/0029-7844(96)00075-0. PMID 8841266.
  • Siperstein AE, Berber E, Morkoyun E (February 2002). "The use of the harmonic scalpel vs conventional knot tying for vessel ligation in thyroid surgery". Arch Surg. 137 (2): 137–42. doi:10.1001/archsurg.137.2.137. PMID 11822946.