Hazardous Substances Data Bank

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TOXNET: Hazardous Substances Data Bank
Description Chemical pharmacology and toxicology data
Data types
  • 5000+ potentially hazardous chemicals
  • human exposure
  • pharmacology
  • metabolism
  • medications excreted in breastmilk[1]
  • industrial hygiene
  • emergency handling
  • environmental fate
  • regulatory requirements
  • related areas
Organisms Humans & other animals
Research center NCBI
Primary citation Fonger (1995)[2]
Fonger, et al (2014)[3]
Website http://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
License Public domain
Data release
Curation policy Peer-reviewed by the Scientific Review Panel

The Hazardous Substances Data Bank (HSDB) is a toxicology database on the U.S. National Library of Medicine's (NLM) Toxicology Data Network (TOXNET).[2][3] It focuses on the toxicology of potentially hazardous chemicals, and includes information on human exposure, industrial hygiene, emergency handling procedures, environmental fate, regulatory requirements, and related areas. All data are referenced and derived from a core set of books, government documents, technical reports, and selected primary journal literature. All entries are peer-reviewed by a Scientific Review Panel (SRP), members of which represent a spectrum of professions and interests. Current Chairs of the SRP are Dr. Finis Cavender, Toxicology Group, and Dr. Roland Everett Langford, Environmental Fate Group.

The HSDB is organized into individual chemical records, and contains over 5000 such records.[4] It is accessible free of charge via TOXNET. Users can search by chemical or other name, chemical name fragment, CAS registry number and/or subject terms. Recent additions include radioactive materials and certain mixtures, like crude oil and oil dispersants as well as animal toxins. As of November 2014, there are approximately 5,600 chemical specific HSDB records available.[3]


  1. ^ "Drugs and Lactation Database (LactMed)". toxnet.nlm.nih.gov.  This article incorporates text from this source, which is in the public domain.
  2. ^ a b Fonger GC (1995). "Hazardous substances data bank (HSDB) as a source of environmental fate information on chemicals". Toxicology. 103 (2): 137–45. PMID 8545846. doi:10.1016/0300-483x(95)03145-6. 
  3. ^ a b c Fonger GC, Hakkinen P, Jordan S, Publicker S (2014). "The National Library of Medicine's (NLM) Hazardous Substances Data Bank (HSDB): background, recent enhancements and future plans". Toxicology. 325: 209–16. PMC 4195797Freely accessible. PMID 25223694. doi:10.1016/j.tox.2014.09.003. 
  4. ^ Fact Sheet – Hazardous Substances Data Bank (HSDB), National Library of Medicine, September 2006, retrieved 29 August 2009 

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