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The text HeadOn is visible with "Head" in white and "On" in yellow. The text is on a green background. Above the "On" is a registered trademark symbol and below the "Head" is the text "Headache Relief" in white.

HeadOn is an American brand of homeopathic topical headache products owned by the Florida-based Miralus Healthcare. The brand achieved notoriety as a result of a viral 2006 commercial consisting only of the tagline "HeadOn: Apply directly to the forehead" repeated three times. A previous commercial claimed the product provided headache relief but was pulled after objections from the Better Business Bureau. The commercial garnered widespread criticism for its loudness, lack of information, repetitiveness, and low production value. No clinical trial has ever found evidence for the product's efficacy, and medical experts have widely described it as a placebo.



HeadOn gained notoriety due to its repetitive advertisements on late-night and syndicated television programs, such as on Wheel of Fortune, The Weather Channel, and reruns of Seinfeld.[1][2] In March 2006, the National Advertising Division of the Better Business Bureau objected to an older HeadOn commercial that claimed that HeadOn provided headache relief, citing insufficient evidence that the product was effective.[2][3] The organization threatened to forward the case to the Food and Drug Administration and the Federal Trade Commission.[2] In response, manufacturer Miralus Healthcare removed all factual claims about the product from their commercials.[3]

Miralus Healthcare tested a number of potential commercials using focus groups; the focus groups reportedly recalled ads with repetition much more than with any other method.[4] Despite the largely negative reception to the commercial, Dan Charron, vice president of sales and marketing at Miralus, stated that nobody in the focus groups had told him that the ads were irritating.[5]


The portion of the commercial that elicited widespread media and popular attention

The commercial starts by showing a conservatively dressed woman apply HeadOn on her forehead[1] against a monochromatic background.[6] The tagline "HeadOn: Apply directly to the forehead" is stated three times in a loud monotone voice[1][7] and a large yellow arrow points at her forehead.[4] The commercial then cuts to an image of the product's packaging[4] and either states, "HeadOn is available without a prescription at retailers nationwide"[1] or "available at Walgreens"[6] without describing the product or its purpose.[1]


Responses to the commercial were largely negative, with The Today Show listing it as the worst commercial of 2006.[8] Seth Stevenson of Slate described the commercial as an example of blunt force advertising and opined that its unintentional low production value aesthetic made the ad "mesmerizing".[4] Kate Wagner of The Baffler compared the actor's expression to a "military commander on a Maoist poster" and described the commercial as both "bizarre" and "unsettling".[1] Wagner further said that the commercial was "unlike anything actual humans would reasonably produce to sell something".[1] Dan Neil, writing in the Los Angeles Times, similarly described the commercial as unique for its lack of information and compared it to North Korean propaganda.[5] Both The Today Show and Ad Age described the commercial as "obnoxious",[9][8] and multiple reviewers joked that the commercial gave viewers headaches.[5][4][9]

The commercial was parodied on The Tonight Show with Jay Leno, Saturday Night Live, and The Daily Show With Jon Stewart.[9] The 2008 spoof film Disaster Movie included a parody of the commercial,[10] and other parodies were shared on the online video-sharing platform YouTube.[11] Sales for HeadOn dramatically increased after the advertising campaign, doubling sales year-on-year from 2005 to 2006.[9] The commercial has been described as a highly effective marketing campaign, though it is unclear if Miralus Healthcare ever turned a profit.[12]: 1248 


"Herein lies the genius of HeadOn, a product that promises nothing, builds no expectations, disappoints no one. It's the Hillary Clinton of over-the-counter meds."

Brian Unger, Day to Day[6]

Yale marketing professor Dina Mayzlin argued that the commercial's crudeness and repetitiveness made it an especially effective advertisement.[2] Jeremy Sheff, writing for the Cardozo Law Review, theorized that the ad's repetition was effective because of the tendency for consumers to perceive familiar brands as more beneficial and less risky.[12]: 1278–1280  Ad Age also suggested that the commercial's camp-like style made it the target of free airtime and parody.[9] Wagner theorized that the unintentional nature of the commercial's absurdist humor made it one of the first and most effective instances of a brand employing absurdist advertising tactics.[1] Both Wagner and Stevenson suggested that the brand's relatively unknown status improved the effectiveness of the ad.[1][4] In a piece on the Commercial Advertisement Loudness Mitigation Act, The Atlantic described the commercial as a notorious example of a commercial using loudness as an advertising tactic.[7]


HeadOn is distributed by Miralus Healthcare[2] in an applicator similar to a glue stick[12]: 1247  and sold at prices between five and eight dollars.[12]: 1249  While iris versicolor, white bryony, and potassium dichromate have been listed as its active ingredients,[13][14] the ingredients are in such small dilutions that the product consists almost entirely of wax.[13][15]


HeadOn claims to relieve headaches using homeopathy,[14] a pseudoscientific system of alternative medicine based on diluting active ingredients.[13][16] No clinical trial has ever shown that HeadOn or any of its active ingredients provide headache relief.[14][17] While Miralus claims that the product has been studied, no relevant data has ever been released to the public.[17] Medical experts have widely stated that any perceived headache relief from the product is the result of the placebo effect.[12]: 1248 

The dilution technique employed by the product leaves only trace amounts of its active ingredients,[17][12]: 1247  and no scientific evidence suggests that dilutions are effective in releasing the medicinal properties of any ingredients.[16]

Other products[edit]

Miralus also launched ActivOn in 2006, a similar homeopathic product for arthritis pain,[6][9] RenewIn, a homeopathic brand of energy pills, and PreferOn, a homeopathic scar treatment cream.[12]: 1248 


  1. ^ a b c d e f g h i Wagner, Kate (May 29, 2019). "Apply Directly to the Forehead: Lamenting the death of the truly weird TV ad". The Baffler. Archived from the original on August 3, 2023. Retrieved August 3, 2023.
  2. ^ a b c d e Howard, Theresa (July 31, 2006). "Headache commercial hits parody circuit, well, HeadOn". USA Today. Money, pp. 1b. Archived from the original on August 4, 2023. Retrieved August 3, 2023 – via EBSCOHost.
  3. ^ a b Dakss, Brian (August 2, 2006). "Doctor: 'Head On' No Headache Cure". CBS News. Archived from the original on June 10, 2020. Retrieved May 22, 2020.
  4. ^ a b c d e f Stevenson, Seth (July 24, 2006). "Head Case: The mesmerizing ad for headache gel". Slate. Archived from the original on June 21, 2023. Retrieved August 3, 2023.
  5. ^ a b c Neil, Dan (July 23, 2006). "Ad Nauseam". Los Angeles Times. Archived from the original on August 3, 2023. Retrieved August 3, 2023.
  6. ^ a b c d Unger, Brian (July 10, 2006). "Taking an Annoying Pain Commercial Head On". Day to Day. NPR. Archived from the original on June 12, 2018. Retrieved August 3, 2023.
  7. ^ a b Garber, Megan (December 13, 2012). "Rejoice! The End of Ads That Yell at You". The Atlantic. Archived from the original on August 3, 2023. Retrieved August 3, 2023.
  8. ^ a b Cooper, Gael Fashingbauer (August 22, 2006). "Best and worst commercials of the year". Today. Archived from the original on October 6, 2021. Retrieved August 3, 2023.
  9. ^ a b c d e f Frazier, Mya (September 24, 2007). "This Ad Will Give You a Headache, but It Sells". Ad Age. Archived from the original on August 3, 2023. Retrieved August 3, 2023.
  10. ^ Adie, Sarah (October 24, 2022). "What Can Be Learned By The Worst Medicine Advert?". Voicentric. Archived from the original on August 21, 2023. Retrieved December 20, 2022.
  11. ^ "Headache remedy becomes pop culture phenom". United Press International. July 31, 2006. Retrieved August 3, 2023.
  12. ^ a b c d e f g Sheff, Jeremy N. (September 22, 2010). "Biasing Brands". Cardozo Law Review. Benjamin N. Cardozo School of Law. 32: 1245–1314. SSRN 1681187. Archived from the original on August 4, 2023. Retrieved August 4, 2023.
  13. ^ a b c Randi, James (July 28, 2006). "Head On Into Quackery". Swift (Newsletter). Archived from the original on August 22, 2006. Retrieved July 28, 2006.
  14. ^ a b c Redfearn, Suz (September 26, 2006). "Head Rub". The Washington Post. Archived from the original on March 5, 2016. Retrieved August 3, 2023.
  15. ^ Salas, Randy A.; Ward, Bill (February 7, 2008). "Hooey or True-y?". Star Tribune. Archived from the original on August 10, 2023. Retrieved August 8, 2023.
  16. ^ a b Grimes, David Robert (2012). "Proposed mechanisms for homeopathy are physically impossible". Focus on Alternative and Complementary Therapies. 17 (3): 149–155. doi:10.1111/j.2042-7166.2012.01162.x.
  17. ^ a b c "Headache drug lacks evidence". Consumer Reports. September 2007. Archived from the original on August 19, 2007. Retrieved January 23, 2008.

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