Bosco was born in Avignon, Vaucluse into a family of Provençal, Ligurian and Piedmontese origin. Through his father, he was related to Saint John Bosco, of whom he wrote a biography. His novels for adults and children provide a sensitive evocation of Provençal life. In 1945 he was awarded the Prix Renaudot for his novel Le Mas Théotime (The Farm Théotime). Other awards he received were the Prix des Ambassadeurs in 1949, the Grand prix national des Lettres in 1953, the Prix de l'Académie de Vaucluse in 1966, the Grand prix de la Mediterranée in 1967, and the Grand prix de l'Académie française in 1968. He died in Nice and was buried at the cemetery of Lourmarin.