Henry M. Fales

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Henry M. Fales
Born (1927-02-12)February 12, 1927
New York City, United States
Died October 28, 2010(2010-10-28) (aged 82)
Silver Spring, Maryland, United States
Nationality American
Alma mater Rutgers University
Known for natural substances identification, bioanalytical chromatography and mass spectrometry
Scientific career
Fields Chemistry
Institutions National Institutes of Health
Doctoral advisor Roderick Barnes

Henry M. Fales (February 12, 1927, New York, NY – October 28, 2010, Silver Spring, MD) was an American organic chemist and mass spectrometrist.[1][2] He authored and co-authored over 350 scientific publications on natural substances and biochemistry and was one of the pioneers in bioanalytical mass spectrometry.

Academic career[edit]

Fales obtained his PhD from Rutgers University. He worked at the National Heart, Lung, and Blood Institute of the National Institutes of Health in Bethesda, Maryland, since 1954, first as Chief of the Laboratory of Biophysical Chemistry and later as Chief of the Laboratory of Applied Mass Spectrometry.[3] Under his direction, the Laboratory of Chemistry in NHLBI became a world-renowned center for structural chemistry during the 1960s, integrating nmr, x-ray crystallography and mass spectrometry. Fales and coworkers also began a reference library of molecular weights which was incorporated into the Merck Index.[4]

He served on the editorial boards for the Journal of Mass Spectrometry, the Journal of the American Society for Mass Spectrometry, Analytical Chemistry and Bioanalytical Chemistry. He served on the advisory panel on Chemistry of the National Science Foundation. H. M. Fales held several functions in the Board of Directors of the American Society for Mass Spectrometry including President.[5]


Fales received several awards including Chromatographer of the Year of the Washington Chromatography Discussion Group (1973), DHEW Superior Service Awards (1973, 1986), the Hillebrand Prize from the Chemical Society of Washington in 1977, and a Professional Service Award of Alpha Chi Sigma, Washington, D.C. (1988). His bibliography up to the year 2005 was published in the Journal of Biomacromolecular Mass Spectrometry.[6]

See also[edit]


  1. ^ Markey, Sanford P. (2011). "Henry M. Fales, February 12, 1927–October 28, 2010". Journal of The American Society for Mass Spectrometry. 22 (4): 789–790. Bibcode:2011JASMS..22..789M. doi:10.1007/s13361-011-0078-z. ISSN 1044-0305. 
  2. ^ "This Week in PNAS". Proceedings of the National Academy of Sciences. 102 (16): 5637–5638. 2005. Bibcode:2005PNAS..102.5637.. doi:10.1073/iti1605102. ISSN 0027-8424. 
  3. ^ "NHLBI Research at the Bethesda Campus: Henry M. Fales". Retrieved 2010-10-30. [permanent dead link]
  4. ^ Sun, Tung; Pedder, D. J.; Fales, H. M. (1973). "Molecular Weight Index of the Merck Index for Mass Spectrometry". Analytical Chemistry. 45 (13): 2297–2300. doi:10.1021/ac60335a006. 
  5. ^ "Presidents of the American Society for Mass Spectrometry". Archived from the original on 2012-08-26. Retrieved 2010-10-30. 
  6. ^ König, Simone, Henry M. Fales. "Reflections on Mass Spectrometry and Other Issues". Biomacromolecular Mass Spectrometry. 1 (2): 99–125. 

External links[edit]