Hepatic fructokinase

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
ketohexokinase (fructokinase)
Identifiers
Symbol KHK
Entrez 3795
HUGO 6315
OMIM 229800
RefSeq NM_006488
UniProt P50053
Other data
EC number 2.7.1.3
Locus Chr. 2 p23.3-23.2
Ketohexokinase
Identifiers
EC number 2.7.1.3
CAS number 9030-50-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.


ATP + Fru    ADP + F1P
ATP + D-fructose → ADP + D-fructose-1-phosphate[1]

Pathology[edit]

A deficiency is associated with essential fructosuria.

References[edit]

External links[edit]