Hepatica (hepatica, liverleaf, or liverwort) is a genus of herbaceous perennials in the buttercup family, native to central and northern Europe, Asia and eastern North America. Some botanists include Hepatica within a wider interpretation of Anemone.
The word hepatica derives from the Latin hepaticus (liver), because the three-lobed leaf was thought to resemble the human liver.
Bisexual flowers with pink, purple, blue, or white sepals and three green bracts appear singly on hairy stems from late winter to spring. Butterflies, moths, bees, flies and beetles are known pollinators.
Noted for its tolerance of alkaline limestone-derived soils, Hepatica may grow in a wide range of conditions; it can be found either in deeply shaded deciduous (especially beech) woodland and scrub or grassland in full sun. Hepatica will also grow in both sandy and clay-rich substrates, being associated with limestone. Moist soil and winter snowfall is a requirement; Hepatica is tolerant of winter snow cover, but less so of dry frost.
Propagation is done by seeds or by dividing vigorous clumps in spring. However, seedlings take several years to reach bloom size, and divided plants are slow to thicken.
Hepatica is named from its leaves, which, like the human liver (Greek hepar), have three lobes. It was once used as a medicinal herb. Owing to the doctrine of signatures, the plant was once thought to be an effective treatment for liver disorders. Although poisonous in large doses, the leaves and flowers may be used as an astringent, as a demulcent for slow-healing injuries, and as a diuretic.
- Eastern North America 
- Hepatica transsilvanica = Anemone transsilvanica (Fuss) Heuff. Carpathian Mountains, Transylvania
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