Hereditary hyperbilirubinemia

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Hereditary hyperbilirubinemia
Classification and external resources
Specialty endocrinology
ICD-10 E80.4-E80.6
ICD-9-CM 277.4
eMedicine med/1065 med/1066
MeSH D006933

Hereditary hyperbilirubinemia refers to the condition where levels of bilirubin are elevated, for reasons that can be attributed to a metabolic disorder.

An example is Crigler-Najjar syndrome.

Symptoms[edit]

UGT1A1 gene mutations causes the condition. As a result, there can be reduced functionality of the bilirubin-UGT enzyme. Eventually it causes unconjugated hyperbilirubinemia and jaundice as substance accumulates in the body due to the reduced ability of the enzyme.[1]

References[edit]

External links[edit]