Heteroglycan alpha-mannosyltransferase

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heteroglycan alpha-mannosyltransferase
Identifiers
EC number 2.4.1.48
CAS number 37277-57-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a heteroglycan alpha-mannosyltransferase (EC 2.4.1.48) is an enzyme that catalyzes the chemical reaction

GDP-mannose + heteroglycan GDP + 2(or 3)-alpha-D-mannosyl-heteroglycan

Thus, the two substrates of this enzyme are GDP-mannose and heteroglycan, whereas its 3 products are GDP, 2-alpha-D-mannosyl-heteroglycan, and 3-alpha-D-mannosyl-heteroglycan.

This enzyme belongs to the family of glycosyltransferases, to be specific the hexosyltransferases. The systematic name of this enzyme class is GDP-mannose:heteroglycan 2-(or 3-)-alpha-D-mannosyltransferase. Other names in common use include GDP mannose alpha-mannosyltransferase, and guanosine diphosphomannose-heteroglycan alpha-mannosyltransferase.

References[edit]

  • Garancis JC, Ankel H, Ankel E, Schutzbach JS (1970). "Mannosyl transfer in Cryptococcus laurentii". J. Biol. Chem. 245 (15): 3945–55. PMID 5492958.