King's Highway 22, commonly referred to as Highway 22, initially as Provincial Highway 22 and currently as Middlesex and Lambton County Road 22, was a provincially maintained highway in the Canadian province of Ontario. The route was decommissioned as a King's Highway in 1991, and later entirely decommissioned in 1998. The highway connected Highway 7 and Highway 79 near Watford to Highway 4 in London. The road has been entirely downloaded.
The highway starts at Warwick, intersecting from Highway 7 and Highway 79. For 7.4 kilometres (4.6 mi), it is known as Lambton Road 22, then changes to Middlesex Road 22 at Adelaide-Metcalfe, after going through Wisbeach. Here Kerwood Road (Middlesex Road 6) joins the route. At 16.5 kilometres (10.3 mi), Highway 81 intersects with the route. Later at 22.7 kilometres (14.1 mi), Hickory Street (Middlesex Road 39) intersects with the route, shortly followed by Ilderton Road. At 26.2 kilometres (16.3 mi), Komoka Road intersects with the route in Middlesex Centre, followed by Nairn Road (Middlesex Road 17) at 33.8 kilometres (21.0 mi). The route continues into the London Boundary of Middlesex Centre at 39.2 kilometres (24.4 mi). Here the road becomes Fanshawe Park Road in London. Hyde Park Road intersects with the route at 41.0 kilometres (25.5 mi), with Wonderland Road joining the route shortly after at 43.6 kilometres (27.1 mi). The route ends at 46.0 kilometres (28.6 mi) and connects to Highway 4, locally known as Richmond Street.
The highway was built in 1927 as a collector highway to go from Watford to London. In the early 1980s, due to the completion of Highway 402, the road became less popular, until, it was downloaded in 1998. Before the road was downloaded, it was 46.0 kilometres (28.6 mi) in length. The highway was first called Provincial Highway 22, until it was renamed to King's Highway 22 in 1930. In 1947, the road was shortened by 8 kilometres (5.0 mi) as a more direct road alignment had been found. The last gravel sections on the road were paved in 1952. In 1973, it was re-routed through London.