Hisako Ōishi (大石 尚子? Ōishi Hisako, August 26, 1936 – January 4, 2012) was a Japanese politician of the Democratic Party of Japan, a member of the House of Councillors in the Diet (national legislature). She was born in Etajima, Hiroshima, grew up in Kamakura, Kanagawa Prefecture and a graduate of Yokohama National University. She served in the assembly of Kanagawa Prefecture for five terms since 1971 and in the House of Representatives in Diet for two terms since 2000. In the 2005 general election, she lost her electoral district (Kanagawa 4) to Liberal Democrat Jun Hayashi and also failed to win a proportional seat. After that, she made an unsuccessful for the House of Councillors in 2007 when she received 59,718 votes nationwide and ranked 21st on the Democratic list while the Democratic Party only won 20 proportional seats, thereby becoming the top replacement for a seat falling vacant. On December 28, 2007 she took over the seat left vacant by Takashi Yamamoto when he died of cancer.
- "民主・大石尚子参院議員が死去 : 政治 : YOMIURI ONLINE（読売新聞）". Yomiuri.co.jp. Retrieved 2012-01-04.
- おくやみ：大石尚子氏 (in Japanese). fu-hou.com. Retrieved 2012-01-07.
- Yomiuri Shimbun, 2007 election feature: Proportional representation results, Democratic Party
- "profile" (in Japanese). oishihisako.com. Retrieved December 26, 2011.
- 秋山眞之と大石尚子 (in Japanese). oishihisako.com. Retrieved December 26, 2011.
- Official website (in Japanese)
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