The station is an elevated structure with two island platforms serving four tracks above ground. The station building is also connected to the Tokyu Store, a large upscale supermarket, and the reformed Tokyu Department Store on the second floor, which features many individually branded shops as well as a major consumer electronic shop ("Best Denki") as a tenant occupying the entire third floor. The Yokohama Subway consists of a single island platform underground.
Hiyoshi Station opened as one of the original Toyoko Line stations on February 14, 1926. The station was completely rebuilt in 1991 with half-submerged tracks and an elevated station building constructed above the tracks. The adjacent Tokyu Department store opened in 1995. The Yokohama Subway Green Line connected to Hiyoshi Station on March 30, 2008.