|Founder||Fritz Hoffmann-La Roche|
|Products||Pharmaceuticals and diagnostics (List of products)|
|Revenue||CHF 58.323 billion (2020)|
|CHF 18.453 billion (2020)|
|CHF 15.068 billion (2020)|
|Total assets||CHF 86.1 billion (2020)|
|Total equity||CHF 39.8 billion (2020)|
Number of employees
|Parent||Roche Holding AG|
F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally.
The company controls the American biotechnology company Genentech, which is a wholly owned affiliate, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States-based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020 were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, and Maja Oeri a further 5% apart), with Swiss pharma firm Novartis owning a further third of its shares. Roche is one of the few companies increasing their dividend every year, for 2020 as the 34th consecutive year. F. Hoffmann-La Roche is a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA).
Founded in 1896 by Fritz Hoffmann-La Roche, the company was early on known for producing various vitamin preparations and derivatives. In 1934, it became the first company to mass-produce synthetic vitamin C, under the brand name Redoxon. In 1957, it introduced the class of tranquilizers known as benzodiazepines (with Valium and Rohypnol being the best known members). It manufactures and sells several cancer drugs and is a leader in this field. In 1956, the first antidepressant, iproniazid, was accidentally created during an experiment while synthesizing isoniazid. Originally, it had been intended to create a more efficient drug at combatting Tuberculosis. Iproniazid, however, revealed to have its own benefits; some people felt it made them feel happier. It was withdrawn from the market in the early 1960s due to toxic side-effects.
In 1976, an accident at a chemical factory in Seveso, Italy, owned by a subsidiary of Roche, caused a large dioxin contamination; see Seveso disaster. In 1982, the United States arm of the company acquired Biomedical Reference Laboratories for US$163.5 million. That company dated from the late 1960s, and was located in Burlington, North Carolina. That year Hoffmann-La Roche then merged it with all of its laboratories, and incorporated the merged company as Roche Biomedical Laboratories, Inc. in Burlington. By the early 1990s, Roche Biomedical became one of the largest clinical laboratory networks in the United States, with 20 major laboratories and US$600 million in sales.
Roche has also produced various HIV tests and antiretroviral drugs. It bought the patents for the polymerase chain reaction (PCR) technique in 1992. In 1995 the era of highly active anti-retroviral therapy (HAART) was initiated by the United States FDA's approval of Hoffman LaRoche's HIV protease inhibitor saquinavir. Within 2 years of its approval (and that of ritonavir 4 months later) annual deaths from AIDS in the United States fell from over 50,000 to approximately 18,000  On 28 April 1995 Hoffmann-La Roche sold Roche Biomedical Laboratories, Inc. to National Health Laboratories Holdings Inc. (which then changed its name to Laboratory Corporation of America Holdings). Roche acquired Syntex in 1994 and Chugai Pharmaceuticals in 2002.
Oseltamivir is a controversial antiviral drug used to combat avian influenza, commonly known as the bird flu. Roche is the only drug company authorized to manufacture the drug, which was discovered by Gilead Sciences. Roche purchased the rights to the drug in 1996 and in 2005 settled a royalty dispute, agreeing to pay Gilead tiered royalties of 14–22% of annual net sales without adjusting the payments for manufacturing costs, as had been allowed in the original licensing agreement.
On 20 October 2005 Hoffmann-La Roche decided to license other companies to manufacture Oseltamivir.
Also in 2005 Roche acquired the Swiss company GlycArt Biotechnology in order to acquire technology to afucosylate antibodies; one of its products in development was obinutuzumab, which gained FDA approval in November 2013 for the treatment of chronic lymphocytic leukemia.
On 26 March 2009, Roche acquired Genentech for $46.8 billion. On 12 March 2009 Roche agreed to fully acquire Genentech, in which it had held a majority stake since 1990, after eight months of negotiations. As a result of the Genentech acquisition, Roche moved its Palo Alto based research facilities to their campus that straddles the border between Clifton, New Jersey and Nutley, New Jersey while Roche's United States headquarters, located on the New Jersey site since 1929, was moved to Genentech's facility in South San Francisco. Genentech became a wholly owned subsidiary group of Roche on 25 March 2009.
In 2011, the company received the International Society for Pharmaceutical Engineering Facility of the Year Award for Process Innovation for Roche's "MyDose" Clinical Supply project. In March 2011, Roche acquired PVT Probenverteiltechnik GmbH for up to €85 million. In July 2010, Roche acquired mtm laboratories AG for up to 190 million EUR. On October, Roche acquired Anadys Pharmaceuticals, Inc. for $230 million. In December, Roche announced it would acquire Munich-based Verum Diagnostica GmbH, gaining entry to the fastest-growing field in the coagulation diagnostics market.
On 26 June 2012, Roche announced the closure of the Nutley/Clifton campus, which was completed in 2013. The property is in the process of remediation.
On 7 April 2014, Roche announced its intention to acquire IQuum for up to $450 million, as well as the rights to an experimental drug (ORY-1001) from Spanish company Oryzon Genomics for $21 million and up to $500 million in milestone payments. On 2 June, Roche announced its intention to acquire Genia Technologies Inc. for up to $350 million. In August 2014, the company agreed to purchase Californian-based pharmaceutical firm InterMune for $8.3 billion, at $74 a share this represents a 38% premium over the final share closing price, as well as Santaris Pharma A/S for $450 million. In December 2014, the company acquired next-generation sequencing processing company Bina Technologies for an undisclosed sum and Dutalys GmbH a developer of next-generation anti-bodies.
On 16 January 2015, the company announced that they would acquire Trophos for €470 million ($543 million) in order to increase the company's neuromuscular disease presence. The deal will centre on the Phase II and III spinal muscular atrophy drug olesoxime (TRO19622). In April 2015, Roche acquired CAPP Medical, and its chief development of technology for cancer screening and monitoring via the detection of circulating tumor DNA.
In August, the company announced its intention to acquire GeneWEAVE , Inc. for up to $425 million in order to strengthen its microbial diagnostics business. Days later the company acquired Kapa Biosystems, Inc. for $445M, focussing on next generation sequencing and polymerase chain reaction applications. In October 2015, the company acquired Adheron Therapeutics for $105 million (plus up to $475 million in milestone payments).
In January 2016, the company announced it would acquire Tensha Therapeutics for $115 million upfront, with $420 million in contingent payments.
In January 2017, the company acquired ForSight VISION4. In June, the company acquired the diabetes management platform, mySugr GmbH for an undisclosed price. In November Roche acquired Viewics, Inc. In late December the company announced it would acquire Ignyta Inc, expanding its global oncology business.
In February 2018, Roche announced it would acquire Flatiron Health, a business specialising in US cancer data analytics, for $1.9 billion. In June of the same year the company announced it would acquire the outstanding shares of Foundation Medicine for $2.4 billion ($137 per share). Later in September Roche announced its intention to acquire Tusk Therapeutics for up to €655 million ($759 million) expanding Roche's oncology pipeline. Tusk announced that the anti-CD38 antibody it is developing will be spun off to form a new company, Black Belt Therapeutics. In late November, the company announced that Genentech would acquire Jecure Therapeutics, gaining access to Jecure's portfolio of NLRP3 inhibitors developed to fight inflammatory diseases like non-alcoholic steatohepatitis and liver fibrosis.
In February 2019, the business announced it would acquire gene therapy company, Spark Therapeutics, for US$4.3 billion ($114.50 per share) adding Spark's gene therapy portfolio to its previous acquired assets. Spark has an already approved treatment for Leber's congenital amaurosis, Luxturna - priced at US$850,000 per patient. The offer to acquire Spark Therapeutics was extended to May 2019 after Roche was unable to garner majority support from Spark shareholders. A second gene therapy-related action came in December with the US$1.15 billion acquisition of non-United States rights to an investigational duchenne muscular dystrophy gene therapy developed by Sarepta Therapeutics. In November Roche acquired Promedior and its lead treatment - PRM-151 - for the treatment of idiopathic pulmonary fibrosis, for $390 million upfront and another $1 billion in milestone payments.
In March 2020, the Roche Diagnostics division reached a significant milestone with the FDA-approval of its high-volume Sars-CoV-2 diagnostic test, capable of analyzing 1,400-8,800 samples within 24h on the proprietary cobas 6800/8800 molecular testing system. In May the company announced it had acquired US-based Stratos Genomics for an undisclosed amount. In September the business acquired Ireland-based Inflazome, for €380 million, gaining control of its NLRP3 inflammasome inhibitors.
In March 2021, Roche announced it would acquire GenMark Diagnostics for $1.8 billion. Under the terms of agreement, Genmark diagnostics will become a subsidiary and the principle operations will continue to remain in Carlsbad, California. In September, the company announced it would acquire German biotech group, TIB Molbiol, enhancing its molecular diagnostics operations.
This section needs additional citations for verification. (January 2020)
Hoffmann-La Roche is strong in the field pharmaceuticals for cancer treatment, against virus diseases and for treatment of metabolic diseases. The company is the world's largest spender in pharmaceutical R&D.
- Accutane/RoAccutane (isotretinoin), for severe (nodular) acne vulgaris - no longer sold under Accutane brand name but is still available as RoAccutane, other brand names and Isotretinoin generics.
- Actemra/RoActemra (tocilizumab), for rheumatoid arthritis.
- Actimmune (interferon gamma), for chronic granulomatous disease, later sold to Connetics Corporation, then InterMune, after that Vidara Therapeutics and finally Horizon Pharma as of 2019.
- Activase (alteplase), for heart attacks.
- Akynzeo (netupitant/palonosetron), for nausea and vomiting, licensed by Eisai Co. and Helsinn Therapeutics.
- Alecensa (alectinib), for ALK-positive non-small cell lung cancer.
- Aloxi (palonosetron), for nausea and vomiting, licensed by Eisai Co. and Helsinn Therapeutics.
- Anexate (flumazenil), for the reversal of acute benzodiazepine effects.
- Aurorix (moclobemide), for depression.
- Avastin (bevacizumab), for certain malignant tumors.
- Bactrim (trimethoprim/sulfamethoxazole), a sulphonamide antibacterial.
- Boniva/Bonviva (ibandronic acid), for the treatment of osteoporosis in postmenopausal women.
- Camleed (enprostil), for gastric ulcer prevention.
- Cardene (nicardipine), for treatment of stable angina pectoris.
- Cathflo Activase (alteplase), for heart attacks.
- Cellcept (mycophenolate mofetil), for transplant rejection.
- Cotellic (cobimetinib), for melanoma.
- Cymevene (ganciclovir), for cytomegalovirus infection.
- Dalmane/Dalmadorm (flurazepam), for insomnia.
- Dilatrend (carvedilol), for hypertension and congestive heart failure.
- Dormicum (midazolam), for insomnia and procedural sedation and analgesia.
- Erivedge (vismodegib), for basal-cell carcinoma.
- Esbriet (pirfenidone), for idiopathic pulmonary fibrosis.
- Fansidar (sulfadoxine/pyrimethamine), for malaria and toxoplasmosis.
- Fuzeon (enfuvirtide), for salvage therapy of HIV-1 infection.
- Gazyva (obinutuzumab), for chronic lymphocytic leukemia.
- Hemlibra (emicizumab), for haemophilia A.
- Herceptin (trastuzumab), for HER-2 positive breast cancer.
- Hivid (zalcitabine), for HIV-1 infection, later discontinued in 2006.
- Inhibace (cilazapril), for hypertension and congestive heart failure.
- Invirase (saquinavir), for HIV-1 infection.
- Kadcyla (trastuzumab emtansine), for HER-2 positive breast cancer.
- Klonopin/Rivotril (clonazepam), for epilepsy and anxiety disorders.
- Kytril (granisetron), for chemotherapy-induced nausea and vomiting, licensed by GlaxoSmithKline.
- Lariam (mefloquine), for malaria (both prevention and treatment).
- Lexotanil (bromazepam), for anxiety disorders.
- Librax (Chlordiazepoxide/clidinium bromide), treating stomach ulcers, irritable bowel syndrome, or symptoms related to intestinal infection.
- Librium (chlordiazepoxide), for anxiety disorders.
- Lucentis (ranibizumab), for wet age-related macular degeneration (AMD).
- Luxturna (voretigene neparvovec), for Leber's congenital amaurosis.
- MabThera (rituximab), for B-cell chronic lymphocytic leukemia (and other hematological malignancies), non-Hodgkin lymphomas and rheumatoid arthritis.
- Madopar/Prolopa (levodopa/benserazide), for Parkinson's disease.
- Mircera (methoxy polyethylene glycol-epoetin beta), for anaemia associated with chronic kidney disease.
- Naprosyn (naproxen), an NSAID used for pain relief and arthritis treatment.
- Neulastim (pegfilgrastim), for neutropenia.
- Neupogen (filgrastim), for neutropenia.
- Nutropin (somatropin), for growth hormone deficiency.
- Nutropin AQ (somatropin), for growth hormone deficiency.
- Nutropin Depot (somatropin), for growth hormone deficiency, later discontinued in 2004 and replaced by Nutropin AQ.
- Ocrevus (ocrelizumab), for MS.
- Pegasys, (peginterferon alfa-2a) for hepatitis B and C.
- Perjeta (pertuzumab), for HER-2 positive breast cancer.
- Polivy (polatuzumab vedotin), for diffuse large B-cell lymphoma.
- Protropin (somatrem), for growth hormone deficiency, later discontinued in 2004 in favor of its successor, Nutropin.
- Pulmozyme (dornase alfa), for the improvement of pulmonary function in cystic fibrosis.
- Raptiva (efalizumab), for psoriasis, later withdrawn in 2009 due to the risk of PML.
- Recormon/NeoRecormon (epoetin beta), for anemia.
- Rituxan (rituximab), for non-Hodgkin's lymphoma.
- Rocaltrol (calcitriol), for osteoporosis and hypocalcaemia.
- Rocephin (ceftriaxone), a broad-spectrum cephalosporin antibiotic.
- Roferon A (peginterferon alfa-2a), for some hematological malignancies (hairy cell leukemia, chronic myelogenous leukemia), certain solid tumors (including Kaposi's sarcoma), genital warts and chronic hepatitis C.
- Rohypnol (flunitrazepam), for severe insomnia.
- Rozlytrek (entrectinib), for ROS1-positive non-small cell lung cancer and NTRK fusion-positive solid tumors.
- Soriatane/Neotigason (acitretin), for psoriasis.
- Tamiflu (oseltamivir), for influenza A and B (both treatment and prevention).
- Tarceva (erlotinib), for various cancers.
- Tasmar (tolcapone), for parkinson's disease, licensed by Mylan and Bausch Health.
- Tecentriq (atezolizumab), for non-small cell lung cancer.
- TNKase (tenecteplase), for heart attacks.
- Toradol (ketorolac), for pain management.
- Valcyte (valganciclovir), for cytomegalovirus infection.
- Valium (diazepam), for anxiety disorders, alcohol withdrawal, status epilepticus and other conditions.
- Venclexta (venetoclax), for chronic lymphocytic leukemia.
- Versed (midazolam), for insomnia and procedural sedation and analgesia.
- Vesanoid (tretinoin), for acute promyelocytic leukemia.
- Viracept (nelfinavir), for HIV-1 infection, licensed by Pfizer and ViiV Healthcare.
- Xeloda (capecitabine), for breast and colorectal cancer.
- Xenical (orlistat), for obesity.
- Xofluza (baloxavir marboxil), for influenza A and B (both treatment and prevention).
- Xolair (omalizumab), for asthma.
- Zelboraf (vemurafenib), for late-stage V600E BRAF mutation-positive melanoma.
- Zenapax (daclizumab), for the prevention of acute transplant rejection.
Diabetes management products produced by Roche under the Accu-Chek brand include Accu-Chek Mobile, Accu-Chek Aviva, Accu-Chek Compact Plus, Accu-Chek Aviva Expert, Accu-Chek Active, Accu-Chek Advantage, Accu-Chek Performa, Accu-Chek Aviva Nano, Accu-Chek Performa Nano blood glucose monitors. Accu-Chek Spirit and Accu-Chek Combo insulin pumps. Accu-Chek 360 and SmartPix diabetes management software.
Other products include:
Stanley Adams, Roche's World Product Manager in Basel, contacted the European Economic Community in 1973 with evidence that Roche had been breaking antitrust laws, engaging in price fixing and market sharing for vitamins with its competitors. Roche was fined accordingly, but a bungle on the part of the EEC allowed the company to discover that it was Adams who had blown the whistle. He was arrested for unauthorised disclosure — an offence under Swiss law — and imprisoned. His wife, having learnt that he might face decades in jail, committed suicide.
In 1999 the firm pleaded guilty to participation in a worldwide conspiracy to raise and fix prices for vitamins sold in the US and globally. Hoffmann-La Roche paid $500 million in criminal fines to the United States.
In addition to internal research and development activities F. Hoffmann-La Roche is also involved in publicly funded collaborative research projects, with other industrial and academic partners. One example in the area of non-clinical safety assessment is the InnoMed PredTox. The company is expanding its activities in joint research projects within the framework of the Innovative Medicines Initiative of EFPIA and the European Commission.
- "Executive Committee". Roche.com. F. Hoffmann-La Roche. Archived from the original on 14 September 2016. Retrieved 26 November 2016.
- "Roche names new head of $13 billion diagnostics unit". Reuters. 11 June 2019.
- "FDA Grants Roche Breakthrough Therapy Designation on Hemophilia Drug". BioPharm International. UBM. 19 April 2018. Retrieved 20 April 2018.
- "Financial Report 2020" (PDF). Roche Holding. 4 February 2021. Retrieved 5 February 2021.
- "Who are the top 10 pharmaceutical companies in the world? (2020) | Proclinical blogs". Proclinical.
- "Top 10 Oncology Pharma Companies in the World | Market Research Blog". Market Research Reports® Inc. 17 May 2019.
- "Top 20 pharma companies by oncology sales - Top Pharma List - PMLiVE". www.pmlive.com. 16 June 2014.
- "The Pharmaceutical Industry in Figures – 2008 Edition". European Federation of Pharmaceutical Industries and Associations (EFPIA). p. 49. Archived from the original on 16 September 2008. Retrieved 25 August 2008.
- "Roche Biomedical Laboratories, Inc". FundingUniverse.com.
- "HIV Surveillance --- United States, 1981—2008". Retrieved 8 November 2013.
- Laboratory Corp of America Holdings · 10-Q · For 3/31/95, SECInfo.com, Filed On 5/15/95, SEC File 1-11353, Accession Number 920148-95-11
- "Roche, Gilead End Tamiflu Feud". Red Herring. 16 November 2005.
- Kher, Unmesh (19 October 2005). "Why Roche Released Tamiflu". Time. Time Inc. Archived from the original on 22 October 2005. Retrieved 22 May 2008.
- "Roche - Roche acquires Swiss based GlycArt Biotechnology to strengthen expertise in therapeutic antibody research". roche.com. Archived from the original on 5 February 2015. Retrieved 29 April 2015.
- Presentation: GlycArt Biotechnology AG From Inception to trade sale – and what happened after... by Dr. Joël Jean-Mairet. Brussels, March 31, 2011
- Cameron, F; McCormack, PL (January 2014). "Obinutuzumab: first global approval". Drugs. 74 (1): 147–54. doi:10.1007/s40265-013-0167-3. PMID 24338113. S2CID 40983655.
- "Roche buys Ventana". Archived from the original on 5 June 2014. Retrieved 2 June 2014.
- Pollack, Andrew (12 March 2009). "Roche buys Memory Pharmaceuticals". The New York Times. Retrieved 2 June 2014.
- Pollack, Andrew (12 March 2009). "Roche buys Genentech". The New York Times. Retrieved 2 June 2014.
- Pollack, Andrew (5 February 1990). "Genentech-Roche Deal May Spur Similar Ties". The New York Times. Retrieved 11 April 2009.
- Bawden, Tom (13 March 2009). "Roche swallows Genentech in third large drugs deal". The Times. London. Archived from the original on 12 June 2011. Retrieved 11 April 2009.
- Jucca, Lisa; Cage, Sam (26 March 2009). "Roche completes Genentech buy". Reuters. Retrieved 11 April 2009.
- "Roche buys Medingo". Archived from the original on 12 January 2014. Retrieved 2 June 2014.
- "Roche buysBioImagene". Archived from the original on 5 June 2014. Retrieved 2 June 2014.
- "2011 Facility of the Year Category winners". Retrieved 28 June 2012.
- "Roche buys PVT". Archived from the original on 5 June 2014. Retrieved 2 June 2014.
- "Roche buys mtm labs". Archived from the original on 5 June 2014. Retrieved 2 June 2014.
- "Roche buys Anadys". Archived from the original on 5 June 2014. Retrieved 2 June 2014.
- "Roche Acquires Verum Diagnostica GmbH for €11 Million". BioSpace.
- "Roche announces closure of Nutley, NJ site". Archived from the original on 18 May 2013. Retrieved 28 June 2012.
- "Roche buys Constitution Medical". Archived from the original on 2 June 2014. Retrieved 2 June 2014.
- "Genentech Purchases Arrayit Corporation Technology". BioSpace.
- "Roche buys IQuum". Archived from the original on 2 June 2014. Retrieved 2 June 2014.
- Copley, Caroline (7 April 2014). "Roche buys experimental drug rights from Oryson". Reuters. Retrieved 2 June 2014.
- Mulier, Thomas (2 June 2014). "Roche buys Genia". Bloomberg. Retrieved 2 June 2014.
- Michelle Cortez (24 August 2014). "Roche Holding Agrees to Buy InterMune for $8.3 Billion". Bloomberg.com.
- "Roche pays 37% premium on shares for InterMune in US $8.3bn deal". San Francisco News.Net. 24 August 2014. Retrieved 24 August 2014.
- "Roche Bags Santaris Pharma A/S In Deal Worth $450 Million". BioSpace.
- "Roche Acquires Big Data Platform Provider". GEN. 19 December 2014.
- "Roche To Pay Up To $489 Million For Next-Gen Antibody Firm Dutalys". BioSpace.
- "Roche to Buy Trophos for Up-to-$543M". GEN. 16 January 2015.
- "Roche Grabs CAPP Medical, a "Liquid Biopsy" Startup Targeting Cancer". BioSpace.
- "Roche to Acquire GeneWEAVE for Up-to $425M". GEN. 13 August 2015.
- "Roche Acquires Genomic Tools Provider Kapa Biosystems". GEN. 19 August 2015.
- "Roche to Acquire Adheron Therapeutics for $105 Upfront - GEN Genetic Engineering & Biotechnology News - Biotech from Bench to Business - GEN". GEN. 9 October 2015. Retrieved 23 May 2017.
- "Roche Acquires Tensha Therapeutics for $115M Upfront - GEN Genetic Engineering & Biotechnology News - Biotech from Bench to Business - GEN". GEN. 11 January 2016. Retrieved 23 May 2017.
- Inc., ForSight VISION4. "ForSight VISION4, Inc. Announces Acquisition by Roche". prnewswire.com.
- Miller, John (30 June 2017). "Roche buys diabetes app firm in digital health push". Reuters.
- "Roche Scoops Up Bay Area's Viewics Amid Diagnostic Data Push". BioSpace.
- "Roche to buy U.S. cancer drugmaker Ignyta for $1.7 billion". Reuters. 22 December 2017 – via uk.reuters.com.
- "Subscribe to read". Financial Times. Cite uses generic title (help)
- "Roche to buy Flatiron Health for $1.9 billion to expand cancer care..." Reuters. 15 February 2018 – via uk.reuters.com.
- "Roche pays $2.4 billion for rest of cancer expert Foundation Medicine". Reuters. 19 June 2018 – via uk.reuters.com.
- "Roche Acquires Cancer Immunotherapy Developer Tusk Therapeutics". 28 September 2018.
- "Roche buys U.S. biotech Jecure in race for liver disease drugs". Reuters. 27 November 2018 – via uk.reuters.com.
- "Roche 'steps up' for gene therapy with $4.3 billion Spark bet". Reuters. 25 February 2019 – via uk.reuters.com.
- "Roche says its $4.3 billion offer for Spark is still on track for June completion". cnbc.com. 3 April 2019.
- Koltrowitz, Silke; Nadeem, Dania (23 December 2019). "Roche dives deeper into gene therapy with $1.15 billion Sarepta licensing deal". Reuters. Retrieved 24 December 2019.
- "Roche to Acquire Fibrosis-Focused Promedior for up to $1.4 Billion".
- "Promedior Enters into Definitive Merger Agreement to be Acquired by Roche".
- Hale C. (March 2020). "FDA grants Roche coronavirus test emergency green light within 24 hours" FierceBiotech. Retrieved 13 March 2020.
- "Roche buys U.S. Gene sequencing tech company Stratos Genomics". Reuters. 22 May 2020.
- "Roche acquires Stratos Genomics to further develop DNA based sequencing for diagnostic use".
- "Roche Dives into NLRP3 Inflammasome Inhibition with Acquisition of Inflazome". BioSpace.
- "Inflazome Announces Acquisition by Roche". BioSpace.
- "Roche Holding Bilanz, Gewinn und Umsatz | Roche Holding Geschäftsbericht | 855167". wallstreet-online.de. Retrieved 5 November 2018.
- MarketScreener. "ROCHE HOLDING AG : Financial Data Forecasts Estimates and Expectations | ROG | CH0012032048 | MarketScreener". www.marketscreener.com. Retrieved 3 June 2020.
- GmbH, finanzen net. "Roche Financials | Markets Insider". markets.businessinsider.com. Retrieved 3 June 2020.
- Miller, John (19 December 2017). "Roche touts Swiss-led R&D unit after years in Genentech's shadow". Reuters. Retrieved 19 December 2017.
- "Roche stops selling acne drug Accutane". Reuters. 26 June 2009. Retrieved 23 February 2016.
- Mathiason, Nick (25 November 2001). "Blowing the final whistle". The Observer. Retrieved 30 September 2014.
- Corporate Crime Reporter. Corporate Crime Reporter. Retrieved on 2013-11-24.
- "Cartel price announcements: The vitamins industry" (PDF). International Journal of Industrial Organization. 26. 2008.
- Mattes, William B. (2008). "Public Consortium Efforts in Toxicogenomics". In Mendrick, Donna L.; Mattes, William B. (eds.). Essential Concepts in Toxicogenomics. Methods in Molecular Biology. 460. pp. 221–238. doi:10.1007/978-1-60327-048-9_11. ISBN 978-1-58829-638-2. PMID 18449490.
- "InnoMed PredTox Member Organizations". Archived from the original on 26 September 2008. Retrieved 2008-08-25.
- Innovative Medicines Initiative. "IMI Call Topics 2008". IMI-GB-018v2-24042008-CallTopics.pdf. European Commission. Archived from the original on 15 October 2009. Retrieved 25 August 2008.
- Hans Conrad Peyer (1996) Roche – A Company History 1896–1996 Basel: Editiones Roche ISBN 3-907770-59-5
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