Holy Trinity Cathedral is the cathedral church of Tirunelveli Diocese under Church of South India.
- Samuel Morley 1896–1903
- Arthur A Williams 1905–1914
- Harry M Waller 1915–1923
- Norman H Tubbs 1923–1928
- Frederick J Western 1929–1938
- Stephen C Neill 1939–1944 (Founder of Bishopric – CSI Tirunelveli Diocese)
- George T Selwyn 1945–1952
- Augustine G Jebaraj 1953–1970 (First Indian bishop –CSI Tirunelveli Diocese)
- Thomas S Garrett 1971–1974
- S Daniel Abraham 1975–1984
- Jason S Dharmaraj 1985–1999
R Joseph served as the senior pastor of Holy Trinity cathedral from 1987-92.