Homatropine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Homatropine
Homatropine.svg
Clinical data
AHFS/Drugs.com Monograph
MedlinePlus a601006
ATC code
Legal status
Legal status
  • Rx only, not FDA approved, only sold in UK
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
ECHA InfoCard 100.001.561
Chemical and physical data
Formula C16H21NO3
Molar mass 356.26 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation), and as a mydriatic (to dilate the pupil). For Homatropine methylbromide see Methylhomatropine, this is a different medication. Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide salt.

Homatropine is also given as an atropine substitute given to reverse the muscarinic and CNS effects associated with indirect cholinomimetic (anti-AChase) administration.

Side effects[edit]

Contraindications[edit]

References[edit]