Homatropine

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Homatropine
Homatropine.svg
Clinical data
AHFS/Drugs.com Monograph
MedlinePlus a601006
ATC code A02BX03 (WHO) S01FA05 (WHO)
Legal status
Legal status
  • rx only, not FDA approved, only sold in UK
Identifiers
CAS Number 87-00-3 N
PubChem (CID) 6321423
DrugBank DB00725 N
ChemSpider 16498795 YesY
UNII 8QS6WCL55Z YesY
ChEMBL CHEMBL1233442 N
ECHA InfoCard 100.001.561
Chemical and physical data
Formula C16H21NO3
Molar mass 356.26 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Homatropine (Equipin, Isopto Homatropine) is an anticholinergic medication that is an antagonist at muscarinic acetylcholine receptors and thus the parasympathetic nervous system. It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation), and as a mydriatic (to dilate the pupil). For Homatropine methylbromide see Methylhomatropine, this is a different medication. Homatropine is less potent than atropine and has a shorter duration of action. It is available as the hydrobromide salt.

Homatropine is also given as an atropine substitute given to reverse the muscarinic and CNS effects associated with indirect cholinomimetic (anti-AChase) administration.

Side effects[edit]

Contraindications[edit]

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