Hopantenic acid

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Hopantenic acid
Stereo, skeletal formula of hopantenic acid
Hopantenic acid ball-and-stick.png
IUPAC name
4-{[(2R)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino}butanoic acid[citation needed]
18679-90-8 YesY
17097-76-6 (Calcium salt) YesY
ChemSpider 26309 YesY
Jmol-3D images Image
KEGG D08042 YesY
PubChem 28281
Molar mass 233.26 g·mol−1
Related compounds
Related alkanoic acids
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Hopantenic acid (homopantothenic acid) is a central nervous system drug. Formulated as the calcium salt, it is used in the Russian Federation for a variety of neurological, psychological and psychiatric conditions and sold as Pantogam (Russian: Пантогам).[1]


Hopantenic acid is a homolog of pantothenic acid. While pantothenic acid is the amide of D-pantoate and β-alanine, hopantenic acid is the amide of D-pantoate and γ-aminobutyric acid (GABA). This change leads to an additional CH2 in the molecule.[2]

See also[edit]


  1. ^ Pantogam, drugs.com
  2. ^ Kopelevich, V. M.; Evdokimova, G. S. Marieva T. D., Shmuilovich, L. M. (1971). "Synthesis of D-homopantothenic acid". Pharmaceutical Chemistry Journal 5 (9): 534–536. doi:10.1007/BF00771659. 

External links[edit]