Hormone therapy or hormonal therapy is the use of hormones in medical treatment. Treatment with hormone antagonists may also be referred to as hormonal therapy or antihormone therapy. The most general classes of hormone therapy are oncologic hormone therapy and hormone replacement therapy, of which there are various kinds (e.g., for menopause, for male menopause, or for sex change).
Indications[edit]
See also[edit]
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| AR |
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| GPRC6A |
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| Others |
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Indirect
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- Antigonadotropins (e.g., anabolic steroids, estrogens, progestogens, prolactin)
- GnRH agonists (e,g, GnRH, leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Gonadotropins (e.g., FSH, hCG, LH)
- Plasma proteins (ABP, albumin, SHBG)
- Progonadotropins
- Steroidogenesis modulators (e.g., 5α-reductase inhibitors)
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| ER |
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Agonists
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- Steroidal: 3α-Androstanediol
- 3β-Androstanediol
- 3α-Hydroxytibolone
- 3β-Hydroxytibolone
- 7-Oxo-DHEA
- 7α-Hydroxy-DHEA
- 7β-Hydroxyepiandrosterone
- 8β-VE2
- 16α-Hydroxy-DHEA
- 16α-Hydroxyestrone
- 16α-IE2
- 16α-LE2 (Cpd1471)
- 16α-Methylestriol
- Δ4-Androstenedione
- Δ5-Androstenediol
- Abiraterone
- Abiraterone acetate
- 17α-Estradiol (alfatradiol)
- Alestramustine
- Almestrone
- Anabolic steroids (prodrugs; e.g., testosterone, metandienone (methandrostenolone), others)
- Atrimustine
- Bolandiol
- Bolandiol dipropionate
- Cloxestradiol
- Conjugated equine estrogens (e.g., sodium equilin sulfate, sodium equilenin sulfate)
- DHEA
- DHEA-S
- Diosgenin
- Epiestriol
- Epimestrol
- Esterified estrogens (e.g., estrone sulfate, equilin sulfate, equilenin sulfate)
- Estetrol
- Estradiol
- Estramustine
- Estramustine phosphate
- Estrapronicate
- Estrazinol
- Estriol
- Estrofurate
- Estromustine
- Estrone
- Etamestrol (eptamestrol)
- Ethinyl estradiol
- Ethinyl estriol
- Etynodiol diacetate
- Mestranol
- Methylestradiol
- Moxestrol
- Mytatrienediol
- Nilestriol
- Noretynodrel
- Orestrate
- Phytosterols (e.g., β-sitosterol, campesterol, stigmasterol)
- Polyestradiol phosphate
- Promestriene
- Quinestradol
- Quinestrol
- SC-4289
- Non-steroidal: (R)-DPN
- (S)-DPN
- (R,R)-THC
- (S,S)-THC
- 2,8-DHHHC
- Alternariol
- Anethole
- Anol
- Benzestrol
- Bifluranol
- Bisdehydrodoisynolic acid
- Carbestrol
- Chalconoids (e.g., isoliquiritigenin, phloretin, phlorizin (phloridzin), wedelolactone)
- Coumestans (e.g., coumestrol, psoralidin)
- Deoxymiroestrol
- Dianethole
- Dianol
- Diarylpropionitrile
- Dieldrin
- Dienestrol
- Diethylstilbestrol
- Dimestrol (dianisylhexene)
- Doisynoestrol (fenocycline)
- Doisynolic acid
- DY-131 (GSK-9089)
- Efavirenz
- Endosulfan
- ERB-196 (WAY-202196)
- Estrobin (DBE)
- Fenarimol
- Fenestrel
- FERb 033
- Flavonoids (incl. 7,8-DHF, 8-prenylnaringenin, apigenin, baicalein, baicalin, calycosin, catechin, daidzein, daidzin, ECG, EGCG, epicatechin, equol, formononetin, glabrene, glabridin, genistein, genistin, glycitein, kaempferol, liquiritigenin, mirificin, myricetin, naringenin, pinocembrin, prunetin, puerarin, quercetin, tectoridin, tectorigenin)
- Fosfestrol (diethylstilbestrol diphosphate)
- Furostilbestrol
- GSK-4716
- Hexestrol
- Hydroxyestrone diacetate
- Lavender oil
- Lignans (e.g., enterodiol, enterolactone)
- Mestilbol
- Metalloestrogens (e.g., cadmium)
- Methallenestril
- Methestrol
- Methestrol dipropionate
- Methiocarb
- Miroestrol
- Nitrate
- Nitrite
- Paroxypropione
- Pentafluranol
- Prinaberel (ERB-041, WAY-202041)
- Propylpyrazoletriol
- Resorcylic acid lactones (e.g., zearalanone, zearalenol, zearalenone, zeranol (zearalanol))
- Quadrosilan
- SKF-82,958
- Stilbenoids (e.g., resveratrol)
- Synthetic xenoestrogens (e.g., alkylphenols, bisphenols (e.g., BPA, BPF, BPS), DDT, parabens, PBBs, PHBA, phthalates, PCBs)
- Terfluranol
- WAY-166818
- WAY-200070
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Antagonists
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| GPER |
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| Others |
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Indirect
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- Antigonadotropins (e.g., androgens, estrogens, progestogens, prolactin)
- GnRH agonists (e,g, GnRH, leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Gonadotropins (e.g., FSH, hCG, LH)
- Plasma proteins (ABP, albumin, SHBG)
- Progonadotropins
- Steroidogenesis modulators (e.g., aromatase inhibitors)
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| PR |
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mPRs
(PAQRs) |
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| Others |
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Indirect
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- Antigonadotropins (e.g., androgens, estrogens, progestogens, prolactin)
- GnRH agonists (e,g, GnRH, leuprorelin)
- GnRH antagonists (e.g., cetrorelix)
- Gonadotropins (e.g., FSH, hCG, LH)
- Plasma proteins (albumin, transcortin)
- Progonadotropins
- Steroidogenesis modulators
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