Horst Bickel

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Horst Bickel

Horst Bickel (28 June 1918 – 1 December 2000) was a German medical doctor.[1]

With Guido Fanconi, he characterized Glycogen storage disease type XI in 1949.[2]

He was also involved in the development of treatments for phenylketonuria.[1][3] In 1951, Bickel, Evelyn Hickmans and John Gerrard were persuaded by a persistent mother to help her daughter, Sheila, who was suffering from phenylketonuria. They created a diet that was low in phenylalanine and the daughter's condition improved.[4]

Bickel, Gerrard and Hickmans were awarded the John Scott Medal in 1962 for their discovery.[4]

His birthday, 28 June, which he shares with Robert Guthrie, another important person for Phenylketonuria was taken up by the European Society for Phenylketonuria and Allied Disorders Treated as Phenylketonuria to launch the International PKU Day.[5]


  1. ^ a b doctor/52 at Who Named It?
  2. ^ Fanconi G, Bickel H (November 1949). "Die chronische Aminoacidurie (Aminosaeurediabetes oder nephrotisch-glukosurischer Zwergwuchs) bei der Glykogenose und der Cystinkrankheit". Helv Paediatr Acta. 4 (5): 359–96. PMID 15397919.
  3. ^ Scheibenreiter S, Tiefenthaler M, Hinteregger V, et al. (July 1996). "Austrian report on longitudinal outcome in phenylketonuria". Eur. J. Pediatr. 155 Suppl 1: S45–9. doi:10.1007/PL00014248. PMID 8828608.
  4. ^ a b Marelene Rayner-Canham, Geoff Rayner-Canham (2008), "Evelyn Hickmans", Chemistry was Their Life: Pioneer British Women Chemists, 1880–1949, World Scientific, p. 198, ISBN 9781908978998
  5. ^ "PKU Day - E.S.PKU". E.S.PKU. Retrieved 2018-11-23.