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HubMed is an alternative, third-party interface to PubMed, the database of biomedical literature produced by the National Library of Medicine.[1] Features include relevance-ranked search results, direct citation export, tagging and graphical display of related articles.[2][3]


  1. ^ Eaton AD (2006). "HubMed: a web-based biomedical literature search interface". Nucleic Acids Res. 34 (Web Server issue): W745–7. doi:10.1093/nar/gkl037. PMC 1538859Freely accessible. PMID 16845111. 
  2. ^ von Isenburg, Megan (1 January 2007). "HubMed". Journal of the Medical Library Association. 95 (1): 95–97. ISSN 1536-5050. PMC 1773043Freely accessible. 
  3. ^ Shultz, Mary (October 2007). "Comparing test searches in PubMed and Google Scholar". Journal of the Medical Library Association : JMLA. 95 (4): 442–445. doi:10.3163/1536-5050.95.4.442. PMC 2000776Freely accessible. PMID 17971893. 

1. Giardiello FM, Brensinger JD, Tersmette AC, Goodman SN, Petersen GM, Booker SV, Cruz-Correa M, Offerhaus JA: Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 2000, 119: 1447–1453. 2. Hearle N, Schumacher V, Menko FH, Olschwang S, Boardman LA, Gille JJ, Keller JJ, Westerman AM, Scott RJ, Lim W, Trimbath JD, Giardiello FM, Gruber SB,Offerhaus GJ, de Rooij FW, Wilson JH, Hansmann A, Moslein G, Royer-Pokora B,Vogel T, Phillips RK, Spigelman AD, Houlston RS: Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome. Clin Cancer Res 2006, 12: 3209-3215. 3. van Lier MG, Westerman AM, Wagner A, Looman CW, Wilson JH, de Rooij FW,Lemmens VE, Kuipers EJ, Mathus-Vliegen EM, van Leerdam ME: High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome. Gut 2011, 60: 141-147. 4. van Lier MG, Wagner A, Mathus-Vliegen EM, Kuipers EJ, Steyerberg EW, van Leerdam ME: High cancer risk in Peutz-Jeghers Syndrome: A systematic review and surveillance recommendations. Am J Gastroenterol 2010, 105:1258-1246. 5. Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G,Warren W, Aminoff M, Hoglund P, Jarvinen H, Kristo P, Pelin K, Ridanpaa M,Salovaara R, Toro T, Bodmer W, Olschwang S, Olsen AS, Stratton MR, de la Chapelle A, Aaltonen LA: A serine/threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 1998, 391: 184–187. 6. Jenne DE, Reimann H, Nezu J, Friedl W, Loff S, Jeschke R, Muller O, Back W,Zimmer M: Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet 1998, 18: 38–43. 7. Aretz S, Stienen D, Uhlhaas S, Loff S, Back W, Pagenstecher C, McLeod DR,Graham GE, Mangold E, Santer R: High proportion of large genomic STK11 deletions in Peutz-Jeghers Syndrome. Human Mutation 2005, 26(6): 513-519. 8. Wang ZJ, Churchman M, Avizienyte E, McKeown C, Davies S, Evans DG,Ferguson A, Ellis I, Xu WH, Yan ZY, Aaltonen LA, Tomlinson IP: Germline mutations of the LKB1(STK11) gene in Peutz-Jeghers patients. J Med Genet 1999, 36: 365-368. 9. Giardiello FM, Welsh SB, Hamilton SR, Offerhaus GJ, Gittelsohn AM, Booker SV,Krush AJ, Yardley JH, Luk GD: Increased risk of cancer in the Peutz–Jeghers syndrome. N Engl J Med 1987, 316: 1511–1514. 10. Hanks SK, Quinn AM, Hunter T: The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 1988, 1: 42-52. 11. Shaw RJ, Kosmatka M, Bardeesy N, Hurley RL, Witters LA, DePinho RA,Cantley LC: The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress.Pro Natl Acad Sci USA 2004, 101: 3329-3335. 12. Mehenni H, Gehrig C, Nezu J, Oku A, Shimane M, Rossier C, Guex N, Blouin JL,Scott HS, Antonarakis SE: Loss of LKB1 kinase activity in Peutz-Jeghers Syndrome, and evidence for allelic and locus heterogeneity. Am J Hum Genet 1998, 63: 1641-1650. 13. Mehenni H, Resta N, Park JG, Miyaki M, Guanti G, Costanza MC: Cancer risks in LKB1 germline mutation carriers. Gut 2006, 55: 984–990. 14. Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, Peters PJ, Clevers HC: Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 2004, 116:457-466. 15. Forcet C, Etienne-Mannevill S, Gaude H, Fournier L, Debilly S, Salmi M, Baas A,Olschwang S, Clevers H, Billaud M: Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity. Hum Mol Genet 2005, 15:1283-1292. 16. Schumacher V, Vogel T, Leube B, Driemel C, Goecke T, Moslein G, Royer-Pokoa B: STK11 genotyping and cancer risk in Peutz-Jeghers syndrome. J Med Genet 2005,42: 428–435.

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