Hughes-Stovin syndrome

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Hughes-Stovin syndrome is a rare autoimmune disorder of unknown cause that is characterized by the combination of multiple pulmonary artery aneurysms and deep vein thrombosis. It is named after the two British physicians, John Patterson Hughes and Peter George Ingle Stovin, who first described it in 1959. It is a rare variant of Behçet's disease, which entails more general problems with the circulatory system. Most patients are young adult males between the age of 20-40. Common clinical presentations include fever, cough, dyspnoea and haemoptysis. Radiological features are similar to those of Behçet's disease.[1] There is no satisfactory treatment for this disease.

Referenced in the TV Series House Season 6 Episode 10 The Down Low.


  • Multiple pulmonary aneurysms[2]
  • Peripheral venous thrombosis[2]
  • Recurrent fever[2]
  • Chills[2]
  • Haemoptysis[2]
  • Cough[2]


  1. ^ "Hughes stovin syndrome". Medcyclopaedia. GE. Archived from the original on 2012-02-05. 
  2. ^ a b c d e f Chalazonitis; et al. (January 29, 2009). "Hughes-Stovin Syndrome: a case report and review of the literature". National Center for Biotechnology Information. Retrieved November 5, 2011.