Pink announced the album and its lead single "Walk Me Home" in an appearance on The Ellen DeGeneres Show on February 6, 2019. "Walk Me Home" was released on February 20; that same day, she performed the song as part of a medley at the 2019 Brit Awards. It was called a "foot-stomping anthem" as well as an "optimistic departure" from the content of her previous album, Beautiful Trauma. Pink revealed the full cover art of the album on February 28, after having it teased it for several days. On March 21, 2019, the "Walk Me Home" music video was premiered. On March 28, she released "Hustle", alongside the album's pre-order. On April 11, the Cash Cash collaboration "Can We Pretend" was released. On April 22, 2019, the album’s title track was released. That same day, she performed "Walk Me Home" on The Ellen DeGeneres Show. On April 26, she was interviewed on Today Show.
Hurts 2B Human received generally positive reviews from contemporary music critics. At Metacritic, which assigns a normalized rating out of 100 to reviews from mainstream critics, the album received an average score of 71, based on nine reviews.
Hurts 2B Human debuted at number one on the US Billboard 200, with 115,000 album-equivalent units, of which 95,000 were pure album sales. It is Pink's third consecutive US number-one album. In its second week, the album dropped to number six on the chart, earning an additional 36,000 album-equivalent units that week.
In the United Kingdom, Hurts 2B Human debuted at number one on the UK Albums Chart, outselling its closest competitor, The Balance by Catfish and the Bottlemen by 22,000 units. It became her third chart-topping album there. The following week, the album remained at the summit of the chart, and was certified silver by the British Phonographic Industry (BPI), denoting 60,000 sales, and becoming her first album to spend more than one week at the top in the country.
^"Czech Albums – Top 100". ČNS IFPI. Note: On the chart page, select 201918 on the field besides the word "Zobrazit", and then click over the word to retrieve the correct chart data. Retrieved May 6, 2019.