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Micrograph of hyaloserositis of the spleen (sugar-coated spleen). H&E stain.

In pathology, hyaloserositis is the coating of an organ with a fibrous hyaline,[1] resulting from inflammation of the serous membrane (serositis) covering the organ.[2]

The spleen is commonly affected and often referred to as sugar-coated spleen.[3] The liver and heart are also sometimes affected and referred to as frosted liver (or sugar-coated liver) and frosted heart respectively.[1]

Hyaloserositis of the spleen is usually considered benign, i.e. it does not necessitate any treatment.

See also[edit]


  1. ^ a b Hyaloserositis. Online Medical Dictionary. URL: http://cancerweb.ncl.ac.uk/cgi-bin/omd?hyaloserositis. Accessed on: June 21, 2008.
  2. ^ serositis at eMedicine Dictionary
  3. ^ "Sugar-coated spleen". Drugs.com.