Hydrogel dressings use a hydrogel pad in contact with the wound. The gel is mostly water, in a hydrophilic polymer matrix. They are designed to keep the wound slightly moist, releasing water or absorbing exudate. In the slightly moist environment, rodent skin heals faster than in a dry one, from both cuts and partial-thickness burns. There exists little evidence comparing hydrogel dressing to other advanced dressings in humans.[needs update]
Polymers used in hydrogels include chitosan, dextran, alginate/gelatin and collagen/glycosaminoglycan. Other materials include custom polypeptides, and blends such as chitosan/sodium alginate/poly(vinyl acetate).
- Seow, Wei Yang; Salgado, Giorgiana; Lane, E. Birgitte; Hauser, Charlotte A. E. (2016-09-07). "Transparent crosslinked ultrashort peptide hydrogel dressing with high shape-fidelity accelerates healing of full-thickness excision wounds" (PDF). Scientific Reports. 6: 32670. doi:10.1038/srep32670. ISSN 2045-2322. PMC 5013444. Retrieved 2017-02-09.
- Loo, Yihua; Wong, Yong-Chiat; Cai, Elijah Z.; Ang, Chuan-Han; Raju, Ashvin; Lakshmanan, Anupama; Koh, Alvin G.; Zhou, Hui J.; Lim, Thiam-Chye; Moochhala, Shabbir M.; Hauser, Charlotte A.E. (June 2014). "Ultrashort peptide nanofibrous hydrogels for the acceleration of healing of burn wounds". Biomaterials. 35 (17): 4805–4814. doi:10.1016/j.biomaterials.2014.02.047. ISSN 0142-9612. Retrieved 2017-02-09.
- Dumville, Jo C; O'Meara, Susan; Deshpande, Sohan; Speak, Katharine (2013-07-12). "Hydrogel dressings for healing diabetic foot ulcers". Cochrane Database of Systematic Reviews. Chichester, UK: John Wiley & Sons. Retrieved 2017-02-09.