From Wikipedia, the free encyclopedia
Jump to: navigation, search
Systematic (IUPAC) name
Ethyl 4-(3-hydroxyphenyl)-1-methyl-piperidine-4-carboxylate
Legal status
Legal status
CAS Number 468-56-4
ATC code none
PubChem CID 61120
ChemSpider 55068 YesY
Chemical data
Formula C15H21NO3
Molar mass 263.332 g/mol

Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of pethidine (meperidine). Hydroxypethidine is significantly less potent than meperidine as an analgesic, (0.3x meperidine in potency) although it also has NMDA antagonist properties like its close relative ketobemidone.[1]

Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

Hydroxypethidine is under international control under the Single Convention on Narcotic Drugs 1961 and therefore controlled like morphine in most countries; in the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9627 and a 2014 annual aggregate manufacturing quota of 2 grammes. The salt in use is the hydrochloride, with a free base conversion ratio of 0.878. [2]

See also[edit]


  1. ^ Isbell Harris. The addiction liability of some analogues of meperidine. Journal of Pharmacology And Experimental Therapeutics, 1949; 97(2): 182-190
  2. ^ http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html