Hydroxysteroid dehydrogenase

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Steroid numbering.

The hydroxysteroid dehydrogenases are a group of alcohol oxidoreductases that catalyze the dehydrogenation of hydroxysteroids.

There are four types, classified by the number of the carbon acted upon:

Carbon From To
3 pregnenolone progesterone
3 17α-hydroxypregnenolone 17α-hydroxyprogesterone
3 dehydroepiandrosterone androstenedione
11 cortisol cortisone
17 androstenedione testosterone
20 progesterone 20α-dihydroprogesterone

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