Hypervitaminosis E
From Wikipedia, the free encyclopedia
| This article relies largely or entirely upon a single source. (September 2015) |
|
|
This article may lend undue weight to certain ideas, incidents, or controversies. (September 2015) |
| Hypervitaminosis E | |
|---|---|
Tocopherol, or vitamin E.
|
|
| Classification and external resources |
Hypervitaminosis E is a state of vitamin E toxicity. Since vitamin E can act as an anticoagulant and may increase the risk of bleeding problems, many agencies have set a tolerable upper intake levels (UL) for vitamin E at 1,000 mg (1,500 IU) per day.[1] This UL was established due to an increased incidence of hemorrhaging with higher doses of supplemental vitamin E. Doses of vitamin E above the UL can also magnify the antiplatelet effects of certain drugs such as anti-coagulant medications and aspirin, which can cause life-threatening symptoms in ill patients. Hypervitaminosis E may also counteract vitamin K, leading to a vitamin K deficiency.
Signs and symptoms[edit]
- Blotchy skin
- Increased bleeding
- Increased blood level of triglycerides
- Decreased production of thyroid hormones
- Decreased activity of vitamin K
- Increased bleeding from aspirin or anti-coagulant medications