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Hypodermoclysis, which can also be called interstitial infusion or subcutaneous infusion, is the subcutaneous administration of fluids to the body, often saline or glucose solutions.[1]

Hypodermoclysis can be used where a slow rate of fluid uptake is required compared to intravenous infusion. Typically, it is limited to 1 ml per minute, although it is possible to increase this by using two sites simultaneously. The chief advantages of hypodermoclysis over intravenous infusion is that it is cheap and can be administered by non-medical personnel with minimal supervision. It is therefore particularly suitable for home care. The enzyme hyaluronidase can be added to the fluid to improve absorption during hypodermoclysis.[2]

See also[edit]


  1. ^ "hypodermoclysis", Merriam-Webster's medical dictionary online. Retrieved July 19, 2009.
  2. ^ Menahem Sasson, Pesach Shvartzman, "Hypodermoclysis: an alternative infusion technique", American Family Physician, vol. 64, no. 9, pp. 1575-1579 (November 1, 2001).