|Classification and external resources|
Hypoestrogenism, or estrogen deficiency, refers to a lower than normal level of estrogen, the primary sex hormone in women. In general, lower levels of estrogen may cause differences in the breasts, genitals, urinary tract, and skin.
Hypoestrogenism is most commonly found in women who are postmenopausal, have premature ovarian failure, or are suffering from amenorrhea; however, it is also associated with hyperprolactinemia and the use of gonadotropin-releasing hormone (GnRH) analogues in treatment of endometriosis. It has also been linked to scoliosis and young women with type 1 diabetes mellitus.
Presentations of low estrogen levels include hot flashes, headaches, lowered libido, and breast atrophy. Reduced bone density leading to secondary osteoporosis and atrophic changes such as pH change in the vagina is also linked to hypoestrogenism.
- Aromatase deficiency
- Estrogen insensitivity syndrome
- Aromatase excess syndrome
- Sartori, M. G.; Feldner, P. C.; Jarmy-Di Bella, Z. I.; Aquino Castro, R; Baracat, E. C.; Rodrigues De Lima, G; Castello Girão, M. J. (2011). "Sexual steroids in urogynecology". Climacteric. 14 (1): 5–14. doi:10.3109/13697137.2010.508542. PMID 20839956.
- Lara, L. A.; Useche, B; Ferriani, R. A.; Reis, R. M.; De Sá, M. F.; De Freitas, M. M.; Rosa e Silva, J. C.; Rosa e Silva, A. C. (2009). "The effects of hypoestrogenism on the vaginal wall: Interference with the normal sexual response". The Journal of Sexual Medicine. 6 (1): 30–9. doi:10.1111/j.1743-6109.2008.01052.x. PMID 19170834.
- Gonadotropin-releasing hormone agonist-induced hypoestrogenism and blood flows in cerebral arteries.