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Other namesOcular hypotelorism,[1] orbital hypotelorism,[1] hypotelorbitism[2]
Hypotelorism as a result of 18p- syndrome

Hypotelorism is an abnormally decreased distance between two organs or bodily parts, usually pertaining to the eye sockets (orbits), also known as orbital hypotelorism.[1]


It is often a result of fetal alcohol syndrome (FAS), caused by large alcohol intake in the first month of pregnancy.[citation needed]

It can be associated with trisomy 13, which is also known as Patau syndrome,[3] as well as hereditary neuralgic amyotrophy.[4]

It can also be associated with fragile X syndrome and Prader–Willi syndrome.

Metopic synostosis, the early closure of metopic suture during skull development in children, can also cause hypotelorism.

See also[edit]


  1. ^ a b c "Hypotelorism". Medical Dictionary. TheFreeDictionary.com. Retrieved 2008-01-19.
  2. ^ "Metopic Synostosis - Thieme Connect" (PDF). profile.thieme.de. doi:10.1055/b-0034-72774.pdf. Retrieved 2020-01-08.
  3. ^ "Hypotelorism". Medcyclopaedia. GE.
  4. ^ Electromyography and Neuromuscular Disorders, Second Edition. Preston and Shapiro.

External links[edit]