The song was one of two newly recorded tracks included on Eurythmics' second greatest hits package Ultimate Collection and the only one of the two released as a single (the other newly recorded track being the song "Was It Just Another Love Affair?"). The song is an electronicdance tune with uplifting lyrics of empowerment. Its music video featured Lennox and Stewart performing the song in front of many television screens showing scenes from videos spanning their Eurythmics career. Lennox also reprised her "Sweet Dreams (Are Made of This)" image by performing the song in a man's suit (her hair was not shaved and colored orange, however). The music video for the song is directed by Matthew Rolston.
"I've Got a Life" returned Eurythmics to the Top 40 in the UK singles chart for the twenty-fourth time, hitting number fourteen. The song was released as a digital download in the United States, although dance remixes were issued on vinyl to nightclub DJs. The track spent three weeks at number one on the U.S. Hot Dance Club Play chart at the end of 2005 and reached number thirty-one on the U.S. Adult Contemporary chart.