IFNB1

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IFNB1
Protein IFNB1 PDB 1au1.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesIFNB1, IFB, IFF, IFNB, IFN-beta, interferon beta 1
External IDsMGI: 107657 HomoloGene: 1640 GeneCards: IFNB1
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for IFNB1
Genomic location for IFNB1
Band9p21.3Start21,077,105 bp[1]
End21,077,963 bp[1]
RNA expression pattern
PBB GE IFNB1 208173 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002176

NM_010510

RefSeq (protein)

NP_002167

NP_034640

Location (UCSC)Chr 9: 21.08 – 21.08 MbChr 4: 88.52 – 88.52 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interferon beta is a protein that in humans is encoded by the IFNB1 gene.[5] The natural and recombinant protein forms have antiviral, antibacterial, and anticancer properties.[6]

Interferon beta 1a (tradenames: Avonex and Rebif) and Interferon beta 1b (tradenames: Betaseron/Betaferon) are used as drugs.

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000171855 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048806 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: IFNB1 interferon, beta 1, fibroblast".
  6. ^ "IFNB1 recombinant protein".

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Further reading[edit]

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