IL17RA

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IL17RA
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases IL17RA, CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R, interleukin 17 receptor A
External IDs MGI: 107399 HomoloGene: 7378 GeneCards: 23765
RNA expression pattern
PBB GE IL17RA 205707 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014339
NM_001289905

NM_008359

RefSeq (protein)

NP_001276834.1
NP_055154.3

NP_032385.1

Location (UCSC) Chr 22: 17.08 – 17.12 Mb Chr 6: 120.46 – 120.49 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Interleukin 17 receptor A, also known as IL17RA and CDw217 (cluster of differentiation w217), is a human gene.[1]

Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.