IL22RA1

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IL22RA1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases IL22RA1, CRF2-9, IL22R, IL22R1, interleukin 22 receptor subunit alpha 1
External IDs MGI: 2663588 HomoloGene: 10943 GeneCards: IL22RA1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021258

NM_178257

RefSeq (protein)

NP_067081

NP_839988.1
NP_839988

Location (UCSC) Chr 1: 24.12 – 24.14 Mb Chr 4: 135.73 – 135.75 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Interleukin 22 receptor, alpha 1 is a protein that in humans is encoded by the IL22RA1 gene.[3]

Function[edit]

The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10RB/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36.

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.