ING2

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ING2
Protein ING2 PDB 1wes.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases ING2, ING1L, p33inhibitor of growth family member 2
External IDs MGI: 1916510 HomoloGene: 20388 GeneCards: 3622
RNA expression pattern
PBB GE ING2 205981 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001291959
NM_001564

NM_023503

RefSeq (protein)

NP_001278888.1
NP_001555.1

NP_075992.2

Location (UCSC) Chr 4: 183.5 – 183.51 Mb Chr 8: 47.67 – 47.68 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Inhibitor of growth protein 2 is a protein that in humans is encoded by the ING2 gene.[3][4]

Function[edit]

This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Shimada Y, Saito A, Suzuki M, Takahashi E, Horie M (Mar 1999). "Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor". Cytogenetics and Cell Genetics. 83 (3-4): 232–5. doi:10.1159/000015188. PMID 10072587. 
  4. ^ a b "Entrez Gene: ING2 inhibitor of growth family, member 2". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.