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Iroquois homeobox 2
Symbols IRX2 ; IRXA2
External IDs OMIM606198 MGI1197526 HomoloGene56490 GeneCards: IRX2 Gene
Species Human Mouse
Entrez 153572 16372
Ensembl ENSG00000170561 ENSMUSG00000001504
UniProt Q9BZI1 P81066
RefSeq (mRNA) NM_001134222 NM_010574
RefSeq (protein) NP_001127694 NP_034704
Location (UCSC) Chr 5:
2.75 – 2.75 Mb
Chr 13:
72.63 – 72.63 Mb
PubMed search [1] [2]

Iroquois-class homeodomain protein IRX-2, also known as Iroquois homeobox protein 2, is a protein that in humans is encoded by the IRX2 gene.[1][2]


IRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[1]


  1. ^ a b "Entrez Gene: iroquois homeobox 2". 
  2. ^ Ogura K, Matsumoto K, Kuroiwa A, Isobe T, Otoguro T, Jurecic V, Baldini A, Matsuda Y, Ogura T (2001). "Cloning and chromosome mapping of human and chicken Iroquois (IRX) genes". Cytogenet. Cell Genet. 92 (3–4): 320–5. doi:10.1159/000056921. PMID 11435706. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.