IRX4

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IRX4
Identifiers
AliasesIRX4, IRXA3, iroquois homeobox 4
External IDsMGI: 1355275 HomoloGene: 9485 GeneCards: IRX4
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for IRX4
Genomic location for IRX4
Band5p15.33Start1,877,413 bp[1]
End1,887,236 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016358
NM_001278632
NM_001278633
NM_001278634
NM_001278635

NM_018885

RefSeq (protein)

NP_001265561
NP_001265562
NP_001265563
NP_001265564
NP_057442

NP_061373

Location (UCSC)Chr 5: 1.88 – 1.89 MbChr 13: 73.26 – 73.27 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Iroquois-class homeodomain protein IRX-4, also known as Iroquois homeobox protein 4, is a protein that in humans is encoded by the IRX4 gene.[5][6]

Function[edit]

IRX4 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113430 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021604 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: iroquois homeobox 4".
  6. ^ Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE (January 2000). "Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand". Dev. Biol. 217 (2): 266–77. doi:10.1006/dbio.1999.9548. PMID 10625552.

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.