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Iroquois homeobox 4
Symbols IRX4 ; IRXA3
External IDs OMIM606199 MGI1355275 HomoloGene9485 GeneCards: IRX4 Gene
Species Human Mouse
Entrez 50805 50916
Ensembl ENSG00000113430 ENSMUSG00000021604
UniProt P78413 Q9QY61
RefSeq (mRNA) NM_001278632 NM_018885
RefSeq (protein) NP_001265561 NP_061373
Location (UCSC) Chr 5:
1.88 – 1.89 Mb
Chr 13:
73.26 – 73.27 Mb
PubMed search [1] [2]

Iroquois-class homeodomain protein IRX-4, also known as Iroquois homeobox protein 4, is a protein that in humans is encoded by the IRX4 gene.[1][2]


IRX4 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.[1]


  1. ^ a b "Entrez Gene: iroquois homeobox 4". 
  2. ^ Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE (January 2000). "Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand". Dev. Biol. 217 (2): 266–77. doi:10.1006/dbio.1999.9548. PMID 10625552. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.