ITGA10

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ITGA10
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases ITGA10, PRO827, integrin subunit alpha 10
External IDs MGI: 2153482 HomoloGene: 2697 GeneCards: ITGA10
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for ITGA10
Genomic location for ITGA10
Band 1q21.1 Start 145,891,208 bp[1]
End 145,910,189 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001303040
NM_001303041
NM_003637

NM_001081053
NM_001302471

RefSeq (protein)

NP_001289969
NP_001289970
NP_003628

n/a

Location (UCSC) Chr 1: 145.89 – 145.91 Mb Chr 1: 96.65 – 96.66 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Integrin alpha-10 also known as ITGA10 is a protein that in humans is encoded by the ITGA10 gene.[5][6][7]

Function[edit]

Integrins are integral membrane proteins composed of an alpha chain and a beta chain, and are known to participate in cell adhesion as well as cell-surface mediated signalling. The I-domain containing alpha 10 combines with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue.[5]

Related gene problems[edit]

References[edit]

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.